What Is the Role of Conservative Antibiotic Treatment in Early Appendicitis?

Chamisa, Inchien

doi:10.5772/25687

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…All these increase the incidence of drug resistance and total cost of treatment. [6,7] There are no clear cut guidelines or recommendations for the optimal use of AMAs in appendicitis [9]. It is well understood that, whenever patient was switch over from IV AMA to oral, ideally it should be of same group to avoid unnecessary exposure of AMAs to microorganisms.…”

Section: Discussionmentioning

confidence: 99%

Prescription Pattern of Anti Microbial Agents in Patients of Appendicitis Admitted in Tertiary care Teaching Hospital: a Cross Sectional Study

Ghodki

Borade

2014

Int J Med Res Rev

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Introduction: Appendicitis is one of the common conditions which usually require surgical intervention. It is almost always associated with inflammation with bacterial infection, treated either conservatively or surgically. In both situations, different types of antimicrobial agents (AMAs) are used. AMAs are used either in inadequate or over doses. This results in development of antimicrobial resistance in microorganisms and thereby increasing duration of stay, morbidity and cost of treatment. Objective: To Study the Prescription pattern of AMAs in patients of appendicitis admitted in Surgery ward of tertiary care teaching hospital. Method: It was a cross sectional study carried out over a period of six months. Data was collected from cases papers of surgery ward from medical record section. It was analyzed and evaluated on basis of various parameters like demographic distribution, complicated or uncomplicated cases, type of treatment, percentage of AMAs prescribed in order of preference, dose, duration, frequency and route of administration of AMAs (i.e. Rational use), average no. of AMAs per patient, incidence of surgical site infection, duration of stay in hospital, etc. Results: Out of 113 cases of appendicitis, only 33 (29.20%) were treated rationally. Ceftriaxone and cefpodoxime were most frequently used AMAs. Average AMAs prescribed per patient were 3. Average of total duration of stay in hospital was 10 days. Conclusion: AMA prescription policy should be formulated and displayed in surgery ward for complicated and uncomplicated appendicitis cases to promote / facilitate rational prescription.

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Section: Discussionmentioning

confidence: 99%

Prescription Pattern of Anti Microbial Agents in Patients of Appendicitis Admitted in Tertiary care Teaching Hospital: a Cross Sectional Study

Ghodki

Borade

2014

Int J Med Res Rev

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Impact of Family History on Acute Appendicitis – An Iraqi Study at Baghdad Teaching Hospital

2018

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Background: Appendicitis is one of the most common causes of the acute abdomen worldwide, but many patients present with atypical signs and symptoms. The study aimed to evaluate the impact of positive family history in the diagnosis of appendicitis in a limited diagnostic setting. Methods: Gender matched case control study of ratio (1:2) was carried out from July 2016 to September 2016 with a sample size of 300 patients. Cases were patients presented in surgical department with acute abdominal pain diagnosed as having appendicitis for whom appendectomy was performed, while controls were hospital based with other abdominal problems. Data was collected using a questionnaire. Primary analysis was a Chi square (χ2) test and the calculation of odds ratio (OR) for the association between final diagnosis of appendicitis and family history. Results: Females were 55% in both groups. Cases were younger than controls (27.05± 12.58 vs. 42.43±17.39 years). Positive family history of appendectomy was higher among cases (66%) than controls (31.5%). The diagnosis of acute appendicitis was 3.8 times higher among those with positive family history of appendectomy and abdominal pain, with a sensitivity of 66% and a specificity of 66.4%. Cases with more than one relative with family history of appendectomy, increased suspicion by 13 times when compared to those without family history. Conclusion: Positive family history of appendectomy in patients with acute abdominal pain and more than one relative with history of appendicitis can be considered as important parameters in the diagnosis of appendicitis in limited diagnostic setting.

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What Is the Role of Conservative Antibiotic Treatment in Early Appendicitis?

Cited by 2 publications

References 37 publications

Prescription Pattern of Anti Microbial Agents in Patients of Appendicitis Admitted in Tertiary care Teaching Hospital: a Cross Sectional Study

Prescription Pattern of Anti Microbial Agents in Patients of Appendicitis Admitted in Tertiary care Teaching Hospital: a Cross Sectional Study

Impact of Family History on Acute Appendicitis – An Iraqi Study at Baghdad Teaching Hospital

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