What Is the Role of Thiurams in Allergy to Natural Rubber Latex Products?

Profile of Dermatological Disorders Among Workers Involved in Fruit Growing Industry of Kashmir Valley in North India

“…Secondly, thiurams are also a cause of rubber glove allergy as they are accelerators in vulcanization of rubber. [ 16 ] We attributed positive allergic reaction to paraphenylene diamine to presence of this amine in footwear and rubber and increased prevalence of use of black rubber boots and gloves in this group of population. Allergy to nickel sulphate can be attributed to the use of locally made nickel plated handcarts which are used for carrying fruits from the site of packaging in fields to vehicles outside orchards.…”

Occupational dermatitis in a wood restorer with thiuram allergy

“…4 They have been widely used in the industrial production of rubber gloves, working shoes, glasses, and coverings, and the medical literature is rich in articles which describe the adverse cutaneous events which have been reported to affect patients with predisposing factors. 5 Nowadays, the use of thiurams as vulcanization agents and rubber accelerators has plummeted considerably; however, these compounds can still be found in certain types of working gloves which contain butyl rubber. 4 Moreover, thiurams are chemically linked to dithiocarbamates, which are accelerators that are employed extensively in the production of gloves; hence, only a small number of working gloves which are available on the market can be used by people who are allergic to thiurams.…”