What is the best drug treatment for premenopausal women with bleeding irregularities using the levonorgestrel-releasing intrauterine system? A systematic review

Heijden, P. A. H. H. van der; Tibosch, R. M. G.; Geomini, Peggy M.A.J.; Veersema, Sebastiaan; Bullens, Lauren M.; Delvaux, Eugenie; Bui, Bich Ngoc; Bongers, Marlies Y.

doi:10.1080/13625187.2020.1797663

Cited by 3 publications

(2 citation statements)

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“…These synthetic variants of sex steroids affect endogenous estradiol, progesterone, and testosterone levels by binding to sex steroid receptors and initiating feedback loops. 45,46 For example, the intake of OCs decreases free testosterone levels by increasing hepatic production of SHBG thus binding and decreasing biologically active circulating androgens. Additionally, the use of synthetic progestin and estrogen inhibit the ovarian estradiol and progesterone production by suppressing LH and FSH centrally through negative feedback.…”

Section: Hormonal Contraceptivesmentioning

confidence: 99%

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Can hormones get you down? studies on sex steroids and depression

Wit¹

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Chapter 2 Testosterone in human studies: modest associations between plasma and salivary measurements Chapter 3 Plasma androgens and the presence and course of depression in a large cohort of women Chapter 4 Plasma androgens and the presence and course of depression in a large cohort of men Chapter 5 Associations between testosterone and metabolic syndrome in depressed and non-depressed older men and women Chapter 6 Associations of plasma androgens with suicidality among men and women: a 9-year longitudinal cohort study Chapter 7 Impact of estradiol variability and progesterone on mood in perimenopausal women with depressive symptoms Chapter 8 Predictors of irritability symptoms in mildly depressed perimenopausal women Part II: Hormonal contraceptives and depression Chapter 9 Association of use of oral contraceptives with depressive symptoms among adolescents and young women Chapter 10 Association between adolescent oral contraceptive use and future major depressive disorder: a prospective cohort study Chapter 11 Hormonal contraceptive use and depressive symptoms: systematic review and network metaanalysis of randomized clinical trials Chapter 12 Efficacy of oral contraceptive pills for depressive symptoms and overall symptomatology in premenstrual syndrome: pairwise and network metaanalysis of randomized trials

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Section: Hormonal Contraceptivesmentioning

confidence: 99%

“…47 In users of vaginal rings, oral contraceptive pills, and most of the progesterone only contraceptives the majority of ovulations is inhibited. 45,46 In intrauterine device users however, only about 20% of the ovulations is inhibited. 45,46…”

Section: Hormonal Contraceptivesmentioning

confidence: 99%

Can hormones get you down? studies on sex steroids and depression

Wit¹

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FSRH Guideline (March 2023) Intrauterine contraception

2023

BMJ Sex Reprod Health

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U.S. Selected Practice Recommendations for Contraceptive Use, 2024

Curtis,

Nguyen,

Tepper

et al. 2024

MMWR Recomm. Rep.

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Summary The 2024 U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR) addresses a selected group of common, yet sometimes complex, issues regarding initiation and use of specific contraceptive methods. These recommendations for health care providers were updated by CDC after review of the scientific evidence and a meeting with national experts in Atlanta, Georgia, during January 25–27, 2023. The information in this report replaces the 2016 U.S. SPR (CDC. U.S. Selected Practice Recommendations for Contraceptive Use, 2016. MMWR 2016;65[No. RR-4]:1–66). Notable updates include 1) updated recommendations for provision of medications for intrauterine device placement, 2) updated recommendations for bleeding irregularities during implant use, 3) new recommendations for testosterone use and risk for pregnancy, and 4) new recommendations for self-administration of injectable contraception. The recommendations in this report are intended to serve as a source of evidence-based clinical practice guidance for health care providers. The goals of these recommendations are to remove unnecessary medical barriers to accessing and using contraception and to support the provision of person-centered contraceptive counseling and services in a noncoercive manner. Health care providers should always consider the individual clinical circumstances of each person seeking contraceptive services. This report is not intended to be a substitute for professional medical advice for individual patients; when needed, patients should seek advice from their health care providers about contraceptive use.

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What is the best drug treatment for premenopausal women with bleeding irregularities using the levonorgestrel-releasing intrauterine system? A systematic review

Cited by 3 publications

References 13 publications

Can hormones get you down? studies on sex steroids and depression

Can hormones get you down? studies on sex steroids and depression

FSRH Guideline (March 2023) Intrauterine contraception

U.S. Selected Practice Recommendations for Contraceptive Use, 2024

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