What is ‘regeneration’ and who needs it?

Abstract

Regeneration is an ambiguous term with diverse meanings. According to the Oxford English Dictionary, to be regenerated is to be 're-born; brought again into existence; formed anew', no doubt an accurate usage but one that is arguably too narrow. More appropriate is another meaning the OED suggests: 'restored to a better state'. Most definitions of regeneration have been driven, over many times and places, by concern about ageing and the desire, at best, to reverse or, at least, to modify its perceived ill-effects. This article considers what we understand by regeneration and who needs it.

Nerve trunk healing and neuroma formation after nerve transection injury

“…Outside the field of medicine, "regeneration" is an ambiguous term with multiple meanings in both regenerative biology and social science (39,40). Properly speaking, nowadays, the field of "peripheral nerve regeneration" has been innovatively studied by neurobiologists and tissue engineers (3,41).…”