“…However, these subjective measures can be influenced by various factors, leading to difficulties in accurately evaluating disease severity and predicting treatment outcomes. [3][4][5] As a result, there is a need for objective and reliable biomarkers that can aid in the diagnosis, monitoring, and management of IBS. A biomarker for IBS is crucial as it can offer objective measures to aid in the accurate diagnosis, prognosis, and monitoring of the condition, which is particularly challenging due to its multifactorial nature and subjective symptomatology.…”