What Is New in Blood-Gas Analysis?

Blackburn, J. P.

doi:10.1093/bja/50.1.51

Cited by 11 publications

(5 citation statements)

References 61 publications

(51 reference statements)

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“…In this case, the binding of hapten-enzyme conjugates by antihapten antibodies causes a modulation of the enzyme activity in solution. Usually, the modulation involves inhibition of enzyme activity and this inhibition is reversed in an amount proportional to the concentration of analyte in the sample (7,8). Glucose 6-phosphate dehydrogenase (G6PDH) has been the enzyme label most often employed and a wide assortment of simple drug assays based on this system are commercially available from Syva Corp. (Palo Alto, CA).…”

Section: T H Imentioning

confidence: 99%

“…Many methods already have been proposed for continuous monitoring of blood gases, and these techniques have been reviewed by several authors (7)(8)(9)(10)(11). While no method has yet received universal acceptance, considerable emphasis has been placed on inexpensive electrochemical devices that utilize outer gas-permeable membranes to achieve high selectivity.…”

mentioning

confidence: 99%

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Development and analytical performance of tubular polymer membrane electrode-based carbon dioxide catheters

Opdycke¹,

Meyerhoff²

1986

Anal. Chem.

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Section: T H Imentioning

confidence: 99%

mentioning

confidence: 99%

Development and analytical performance of tubular polymer membrane electrode-based carbon dioxide catheters

Opdycke¹,

Meyerhoff²

1986

Anal. Chem.

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“…Presently, an alternative drug to pancuronium for use in renal failure may be fazadinium bromide (Camu and D'Hollander, 1978;Duvaldestin et alii, 1979) although it has a high percentage of renal elimination also (Duvaldestin et alii, 1978); and there is currently discussion about the possibility of it replacing succinylcholine in achieving rapid relaxation (Rowlands and Fidler, 1978;Blackburn and Morgan, 1978). Moreover, its haemodynamic effects are moderate (Pinaud et alii, 1978).…”

Section: Anaesthesiamentioning

confidence: 99%

Heart Surgery in Patients Under Haemodialysis

Gómez-Arnau

Domínguez

Peral

et al. 1981

Australian and New Zealand Journal of Surgery

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Several cases of open‐heart surgery on patients with severe chronic renal failure have been reported in the last few years. The present study reviews the main problems posed by this situation and analyses our recent experience of three successfully managed patients. Emphasis is made on preoperative preparation, drugs employed in anaesthesia, and postoperative management. We conclude that the prognosis of these patients Is good, and that their management is quite similar to that of nephrologically healthy patients.

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“…Blood gas measurement is a monitoring or diagnostic test that is used to determine the levels of partial pressures of oxygen (pO2) and carbon dioxide (pCO2) circulating in the blood [ 1 ]. These values can be used to calculate several biomedical parameters including bicarbonate levels and electrolytes [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of agreement between a noninvasive method for real-time measurement of critical blood values with a standard point-of-care device

Ettrich,

Caballero,

Sakharkar

et al. 2024

PLoS ONE

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The purpose of this work was to investigate the degree of agreement between two distinct approaches for measuring a set of blood values and to compare comfort levels reported by participants when utilizing these two disparate measurement methods. Radial arterial blood was collected for the comparator analysis using the Abbott i-STAT® POCT device. In contrast, the non-invasive proprietary DBC methodology is used to calculate sodium, potassium, chloride, ionized calcium, total carbon dioxide, pH, bicarbonate, and oxygen saturation using four input parameters (temperature, hemoglobin, pO2, and pCO2). Agreement between the measurement for a set of blood values obtained using i-STAT and DBC methodology was compared using intraclass correlation coefficients, Passing and Bablok regression analyses, and Bland Altman plots. A p-value of <0.05 was considered statistically significant. A total of 37 participants were included in this study. The mean age of the participants was 42.4 ± 13 years, most were male (65%), predominantly Caucasian/White (75%), and of Hispanic ethnicity (40%). The Intraclass Correlation Coefficients (ICC) analyses indicated agreement levels ranging from poor to moderate between i-STAT and the DBC’s algorithm for Hb, pCO2, HCO3, TCO2, and Na, and weak agreement for pO2, HSO2, pH, K, Ca, and Cl. The Passing and Bablok regression analyses demonstrated that values for Hb, pO2, pCO2, TCO2, Cl, and Na obtained from the i-STAT did not differ significantly from that of the DBC’s algorithm suggesting good agreement. The values for Hb, K, and Na measured by the DBC algorithm were slightly higher than those obtained by the i-STAT, indicating some systematic differences between these two methods on Bland Altman Plots. The non-invasive DBC methodology was found to be reliable and robust for most of the measured blood values compared to invasive POCT i-STAT device in healthy participants. These findings need further validation in larger samples and among individuals afflicted with various medical conditions.

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What Is New in Blood-Gas Analysis?

Cited by 11 publications

References 61 publications

Development and analytical performance of tubular polymer membrane electrode-based carbon dioxide catheters

Development and analytical performance of tubular polymer membrane electrode-based carbon dioxide catheters

Heart Surgery in Patients Under Haemodialysis

Evaluation of agreement between a noninvasive method for real-time measurement of critical blood values with a standard point-of-care device

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