What High‐Resolution Solid‐State NMR Spectroscopy Can Offer to Organic Chemists

Potrzebowski, Marek J.

doi:10.1002/chin.200329205

Cited by 3 publications

(4 citation statements)

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“…5 Solid-state nuclear magnetic resonance (SSNMR) can probe the local molecular environment in a solid, and is increasingly applied to solid-state chemistry of pharmaceuticals and other organic molecules. 6,7 Vibrational spectroscopy also measures properties on a molecular level, and is sensitive to differences in solid phase. 8 As a whole, the results obtained from these diffractometric and spectroscopic techniques, in conjunction with traditional thermal and physical analysis, offer an effective means for characterizing and understanding polymorphism and solid-state structure.…”

Section: Introductionmentioning

confidence: 99%

Structural analysis of polymorphism and solvation in tranilast

Vogt

Cohen

Bowman

et al. 2005

Journal of Pharmaceutical Sciences

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Section: Introductionmentioning

confidence: 99%

Structural analysis of polymorphism and solvation in tranilast

Vogt

Cohen

Bowman

et al. 2005

Journal of Pharmaceutical Sciences

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“…This conclusion is based on analyses of 13 C ␦ ii parameters available from solid-state NMR measurements and comparison of data for 1 in pure form and embedded in the matrix. It is well known that 13 C CST parameters for carboxyl group (in particular 13 C ␦ 22 ) are very sensitive to change of strength of hydrogen bonding and analysis of intermolecular interactions [18]. Resemblance of 13 C parameters for 1 and 1 embedded in the MALDI matrix (see Supplementary Materials) justify given supra statement.…”

Section: Nmr Study Of Plla/dpe With Maldi-tof Matricesmentioning

confidence: 94%

Solid-state NMR spectroscopy as a tool supporting optimization of MALDI-TOF MS analysis of polylactides

Sroka-Bartnicka

Olejniczak

Sochacki

et al. 2009

J. Am. Soc. Mass Spectrom.

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We report systematic structural studies of poly(l-lactide) (PLLA) employing matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) and solid-state NMR spectroscopy. (13)C cross polarization magic angle spinning (CP/MAS) NMR data for 1,8-dihydroxy-9-anthracenone (DT), 2,5-dihydroxybenzoic acid (DHB), 2-(4-hydroxyphenylazo)-benzoic acid (HABA), and trans-3-indoleacrylic acid (IAA), four matrices commonly used in MALDI-TOF analysis of polymers, were analyzed to test the influence of crystallization conditions (solvent, inorganic salt) on sample morphology. (13)C principal elements of chemical shift tensor (CST) and line-shape analyses were employed to study of the nature of hydrogen bonding and to evaluate the crystallinity and amorphicity of the pure polymer. NMR parameters for PLLA were compared with data for polylactide crystallized with the four matrices under different conditions with the addition of two inorganic salts as cationization agents. This study revealed that the semicrystalline structure of the polymer does not change when it is embedded in the matrix.

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Section: Introductionmentioning

confidence: 99%

“…The rotation of molecules engendered exchange peaks, from which the magnitude of interactions and the molecular rotation angle can be calculated. 9,10 The homo-nuclear and hetero-nuclear 2D correlated solid-state NMR spectroscopy was found to be of particular value in studies of organic-inorganic complex structures.Sozzani et al determined by means of 2D solid-state NMR the structure and interactions of the MgCl 2 þ EtOH adduct (a catalyst support for Ziegler-Natta polymerization). 11 Closer to the PNC technology were more recent publications from the group.…”

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confidence: 99%

Synthetic, layered nanoparticles for polymeric nanocomposites (PNCs)

Utracki

Sepehr

Boccaleri

2007

Polymers for Advanced Techs

379

252

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Synthetic, layered nano-particles for polymeric nanocomposites (PNC's)Utracki, L. A.; Sepehr, M.; Boccaleri, E.Contact us / Contactez nous: nparc.cisti@nrc-cnrc.gc.ca.http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=fr L'accès à ce site Web et l'utilisation de son contenu sont assujettis aux conditions présentées dans le site Web page / page Web http://dx.doi.org/10.1002/pat.852 http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=15774991&lang=en http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=15774991&lang=fr LISEZ CES CONDITIONS ATTENTIVEMENT AVANT D'UTILISER CE SITE WEB. READ THESE TERMS AND CONDITIONS CAREFULLY BEFORE USING THIS WEBSITE.Access and use of this website and the material on it are subject to the Terms and Conditions set forth at http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=en This review discusses preparation and use of the synthetic layered nanoparticles in polymer matrices, i.e., in the polymeric nanocomposites (PNCs). Several types of synthetic or semi-synthetic layered materials are considered, namely the phyllosilicates (clays), silicic acid (magadiite), layered double hydroxides (LDHs), zirconium phosphates (ZrPs), and di-chalcogenides. The main advantage of synthetic clays is their chemical purity (e.g. absence of amorphous and gritty contaminants, as well as arsenic, iron, and other heavy metals), white to transparent color that assures reproducibly of brightly colored products, as well as a wide range of aspect ratios, p ¼ 20 to £6000. Several large scale production facilities have been established. The synthetic clay and LDH industries are oriented toward big volume markets: catalysis, foodstuff, cosmetics, pharmaceuticals, toiletry, etc. The use of these materials in PNCs is limited to synthetic clays and LDHs, mainly for reinforcement, permeability control, reduction of flammability, and stabilization, e.g. during dehydrohalogenation of chlorinated macromolecules. The use of lamellar ZrPs and di-chalcogenides is at the laboratory stage of functional polymeric systems development, e.g. for electrically conductive materials, catalysts or support for catalysts, in photochemistry, molecular and chiral recognition, or in fuel cell technologies, etc. Copyright # 2007 John Wiley & Sons, Ltd.KEYWORDS: polymeric nanocomposites; nanoparticles; clay; layered double hydroxides; matrix POLYMERS FOR ADVANCED TECHNOLOGIES Polym. Adv. Technol. 2007; 18: 1-37 Published online in Wiley InterScience (www.interscience.wiley.com) DOI: 10.1002/pat.852 AUTHORS' BIOGRAPHIESDr Leszek A. Utracki was born and educated (up to Habilitation) in Poland. After the post-doctoral stage at USC in Los Angeles with Robert Simha he settled in Canada. His passionate research interest has been within the field of thermodynamics, rheology and processing of multicomponent, multiphase polymeric systems. During the 55 years in the profession he has published several hundred articles, book chapters, books, patents, etc., which has placed him on the ISI li...

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What High‐Resolution Solid‐State NMR Spectroscopy Can Offer to Organic Chemists

Cited by 3 publications

References 40 publications

Structural analysis of polymorphism and solvation in tranilast

Structural analysis of polymorphism and solvation in tranilast

Solid-state NMR spectroscopy as a tool supporting optimization of MALDI-TOF MS analysis of polylactides

Synthetic, layered nanoparticles for polymeric nanocomposites (PNCs)

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