What happens to temporal hypometabolism contralateral to side of surgery in patients with bilateral temporal hypometabolism?

Are low-grade gliomas of mesial temporal area alone?

“…It has been shown that temporal neocortex even appeared normal on preoperative MRI may show pathological tissues. [16] Experience from TLE surgery has proven dual pathology, especially FCD, on the temporal neocortex in patients with pure HS[2,17] and it has been claimed that continuation of seizure after selective resection of mesial temporal area may be due to the presence of dual pathology on the unresected temporal neocortex. With the same sense, dual pathology has been found in the temporal neocortex in patients who had undergone resection of glioneuronal tumors from the mesial temporal area[12] suggesting that epileptogenic zone in these kinds of tumors is more extensive than appeared on preoperative MRI.…”

“…The authors of the current paper do not aim to compare seizure and oncological and even neuropsychological results from anterior temporal resection with selective resections. Rather the aim of this paper is to show whether temporal neocortex which appears normal on the preoperative MRI has pathological tissues in patients with pure mesial temporal LGG since histopathological studies proved the dual pathology on the temporal neocortex in patients with MTLE-HS[2,16] and LGG of mesial temporal area. [12] All patients included here were seizure-free, and no recurrence was noted because of supra-total resection (anterior temporal resection).…”

“…[17] This shift mainly depends on pathological tissues found in temporal cortex of patients who had undergone standard temporal resection in patients with MTLE-HS. [2,16] Furthermore, in some reports that dual pathology was found in temporal cortex which appeared normal on preoperative MRI in patients with mesial temporal LGG after surgery. [16] They underlined that continuation of seizure after lesionectomy alone in patients with mesial temporal lobe LGG after surgery may be due to the existence of cortical pathology and suggested tailored resection with the guidance of electrophysiological studies.…”

“…[16] They underlined that continuation of seizure after lesionectomy alone in patients with mesial temporal lobe LGG after surgery may be due to the existence of cortical pathology and suggested tailored resection with the guidance of electrophysiological studies. [2,12,16,17]…”

“…[16] ey underlined that continuation of seizure after lesionectomy alone in patients with mesial temporal lobe LGG after surgery may be due to the existence of cortical pathology and suggested tailored resection with the guidance of electrophysiological studies. [2,12,16,17] With this respect, we conducted a prospective study of patients with pure mesial temporal LGG treated by surgery: all underwent standard anterior temporal resection to see whether temporal cortex which was normal on preoperative MRI has any pathological tissue in addition to mesial temporal LGG.…”