What does the increasing prevalence of obesity mean for the management of asthma and airways disease?

Simpson, Jodie L.; Scott, Hayley A.

doi:10.1590/1806-3713/e20200048

Cited by 2 publications

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References 11 publications

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“…Moreover, asthma and OSAS are both risk factors for developing the other disease [6]. Relationship between asthma and obesity probably represents a combination of mechanical and inflammatory processes [78].…”

Section: Obese Phenotype In Asthmamentioning

confidence: 99%

Obesity and the Lung: What We Know Today

et al. 2020

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Obesity is becoming more and more prevalent especially in Western industrial nations. The understanding of adipose tissue as an endocrine organ as well as the detection of adipocytokines – hormones that are secreted from the adipose tissue – gave reason to examine the interactions between adipose tissue and target organs. These efforts have been intensified especially in the context of bariatric surgery as promising weight loss therapy. Interactions between the lung and adipose tissue have rarely been investigated and are not well understood. There are obvious mechanical effects of obesity on lung function explaining the associations between obesity and lung diseases, in particular obesity hypoventilation syndrome, obstructive sleep apnea syndrome, asthma, and chronic obstructive pulmonary disease. The rise in the prevalence of obesity affects the epidemiology of pulmonary diseases as well. The aim of this review is to summarize the current knowledge on interactions, associations, and consequences of obesity and weight loss on lung function and lung diseases. Based on these data, areas for future research are identified.

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Section: Obese Phenotype In Asthmamentioning

confidence: 99%