What does <scp>SARS‐CoV</scp>‐2 tell us about the aetiology of environmental triggers for diabetes in children and young people?

Ponmani, Caroline; Lyttle, Mark D.; Barrett, Michael; Hulse, Tony; Nijman, Ruud G.; Roland, Damian; ,

doi:10.1111/apa.16971

Acta Paediatrica

2023

DOI: 10.1111/apa.16971

|View full text |Cite

What does SARS‐CoV‐2 tell us about the aetiology of environmental triggers for diabetes in children and young people?

Caroline Ponmani,

Mark D. Lyttle,

Michael Barrett

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 13 publications

(41 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Characteristics of children presenting with new onset diabetes and DKA in the COVID-19 pandemic: a national cohort study

Ponmani,

Roland,

Lyttle

et al. 2024

Front. Disaster Emerg. Med.

View full text Add to dashboard Cite

ObjectivesThe objective of this study was to evaluate the characteristics of children presenting with new onset diabetes and diabetic ketoacidosis (DKA) in the first COVID pandemic year, compared to pre-pandemic evidence and identify the factors associated with DKA at diagnosis.DesignRetrospective medical record review.SettingForty-nine pediatric Emergency Departments (EDs) across the UK and Ireland.PatientsAll children aged 6 months to 16 years presenting to EDs with new onset diabetes and DKA, during the COVID-19 pandemic (1 March 2020–28 February 2021) and the preceding year (1 March 2019–28 February 2020).ResultsThere were increases in children presenting with new onset diabetes in DKA (395–566, 43%) and severe DKA (141–252, 79%) in the first COVID pandemic year, with patient characteristics similar to the pre-pandemic period. Healthcare seeking delay did not appear to be the sole contributing factor to DKA during the COVID pandemic. The median duration of symptoms of 14 days for both children who presented with and without DKA and were similar across both years; those in severe DKA had shorter median duration of 7 days (IQR: 5–21 days).ConclusionsThere were significant increases in children with new onset diabetes presenting with DKA in the first COVID pandemic year. Increased DKA rates and severity despite a constant median symptom duration suggest a multifactorial process. Studies to determine checkpoints for intervention between symptom onset and diagnosis of diabetes are vital to mitigate the high incidence of DKA in new onset diabetes.

show abstract

Characteristics of children presenting with new onset diabetes and DKA in the COVID-19 pandemic: a national cohort study

Ponmani,

Roland,

Lyttle

et al. 2024

Front. Disaster Emerg. Med.

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

What does SARS‐CoV‐2 tell us about the aetiology of environmental triggers for diabetes in children and young people?

Cited by 1 publication

References 13 publications

Characteristics of children presenting with new onset diabetes and DKA in the COVID-19 pandemic: a national cohort study

Characteristics of children presenting with new onset diabetes and DKA in the COVID-19 pandemic: a national cohort study

Contact Info

Product

Resources

About