“…Fibrotic tissue formation is likely due to large micromotion between the stem and the hosting bone (Pilliar et al, 1986b), while peri-prosthetic bone damage is likely due to excessive strains on the host bone (Morgan and Keaveny, 2001). There is evidence that patient and surgical factors, including anatomy (Heller et al, 2001;Renner et al, 2016;Umeda et al, 2003), bone material properties (Wong et al, 2005), stem position (Bah et al, 2009;Bah et al, 2011;Dopico-Gonzalez et al, 2009), size (Al-Dirini et al, 2018) and the extent of the cortical contact (Viceconti et al, 2001b) influence micromotion, peri-prosthetic bone strains and hence, the primary stability of femoral stems.…”