What Do Students in Pharmacy and Medicine Think About Pharmacogenomics and Personalized Medicine Education? Awareness, Attitudes, and Perceptions in Malaysian Health Sciences

Siamoglou, Stavroula; Koromina, Maria; Moy, Foong Ming; Mitropoulou, Christina; Patrinos, George P.; Vasileiou, Konstantinos

doi:10.1089/omi.2020.0178

Cited by 13 publications

(17 citation statements)

References 16 publications

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“…Attitude scores did not differ by gender, medical school year or interest in a career involving research.Our ndings also revealed signi cant ethical concerns regarding precision medicine among our respondents, majority of which bothered around the use of genomic testing results by governments or corporate bodies, possible widening of socioeconomic disparities, employability and insurance discrimination.Interestingly, respondents were least worried about violation of privacy and con dentiality and ethnic/racial discrimination. These concerns closely re ected similar ndings by Siamoglou et al (2021) and Mahmutovic et al (2018)(1,30). Students in Mahmutovic et al (2018), however, were most concerned about privacy and con dentiality.…”

supporting

confidence: 84%

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-Sectional Survey in Lagos, Nigeria

Ogamba

Roberts

Ajudua

et al. 2023

Preprint

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Background Advances in precision medicine in Nigeria call for a need to improve genomics education and competency among healthcare practitioners to facilitate clinical translation. Due to the paucity of research in this area, this study aimed to assess the preparedness of Nigerian medical students to integrate precision medicine into their clinical practice. Methods This was an institution-based cross-sectional study of 300 4th to 6th-year medical students attending the two fully-accredited colleges of medicine in Lagos, Nigeria between April and October 2022 using an adapted tool administered via Google Forms. The survey assessed awareness, perceived knowledge, ability, and attitudes toward precision medicine as well as ethical concerns and perceptions about their education in precision medicine. Results Awareness of precision medicine terminologies was high (92.0%). Respondents had above-average median knowledge and ability scores and high median attitude scores. Respondents expressed concerns mostly about the misuse of genomic data (35.7%) and the possible widening of socioeconomic disparities (34.0%). Although respondents thought that it is important to learn about precision medicine (65.0%), only 11.3% felt that their education had adequately prepared them. Conclusion These highlight a poor sense of preparedness and the need to improve precision medicine education among Nigerian medical students.

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supporting

confidence: 84%

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-Sectional Survey in Lagos, Nigeria

Ogamba

Roberts

Ajudua

et al. 2023

Preprint

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“…The main objective of pharmacogenomics is to assess the impact of an individuals’ genetic makeup on drug efficacy and tolerance, and it is a vital factor in the new era of tailored medicine [ 18 ]. The field of pharmacogenomics is quite fresh in the Middle East.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, studies have discovered that genetic variation in Saudi Arabia is high for a variety of causes, emphasizing the importance of pharmacists’ education in pharmacogenomics [ 11 , 12 ]. There have been several reports published previously from around the world to study the knowledge or attitude of pharmacy students towards pharmacogenomics [ 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. As per our knowledge, no such research/survey has been conducted so far in Riyadh to examine the impact of different attributes in knowledge and attitude towards pharmacogenomics in pharmacy students.…”

Section: Introductionmentioning

confidence: 99%

Knowledge, Attitude and Perception of Pharmacy Students towards Pharmacogenomics and Genetics: An Observational Study from King Saud University

Arafah

Rehman

Alrabiah

et al. 2022

Genes

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Pharmacists are considered among the most accessible healthcare workers in fundamental positions to implement new clinical initiatives, such as pharmacogenomics services. The scope of pharmacogenomics in improving health outcomes and the quality of health care is well-known. Implementation of such initiatives requires adequate knowledge, perception, and positive attitudes among pharmacists. A study was conducted on pharmacy students at King Saud University in Riyadh to analyze their attitudes, knowledge, and perceptions concerning pharmacogenomics to explore the feasibility of establishing full-time pharmacogenomics instruction and services. A cross-sectional study was carried out in one of the significant pharmacy schools of Saudi Arabia, using a simple questionnaire-based survey in pharmacy students pursuing Bpharm and PharmD courses to obtain preliminary information about pharmacogenomics among the surveyed population. The study’s secondary objective was to determine the perceived belief about pharmacogenomics implementation in clinical practice. Out of the total of 552 participants, 41.8% correctly defined pharmacogenomics and 81.3% understood that genetic change could lead to adverse reactions. More than half of the participants agreed that the FDA recommends pharmacogenomics testing for certain drugs. The knowledge about a year of use of pharmacogenomics in clinical practice was found to be very low; only 15.2% could correctly answer. Only 60% of students agreed on pharmacogenomics testing for selecting the therapy with the most negligible adverse effects. Due to the limited knowledge about and understanding of pharmacogenomics, there is a lack of interest among pharmacy students in implementing pharmacogenomics testing in clinical practice. Our study highlights the need for improving pharmacy students’ knowledge about pharmacogenomics and pharmacogenetics so that the implementation of pharmacogenomics testing in clinical practice will become easier. There is a need to introduce an up-to-date curriculum for pharmacy courses other pharmacogenomics-based health education programs in Saudi Arabia.

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“…The instrument employed in this research was a validated questionnaire elaborated by the Laboratory of Pharmacogenomics and Individualized Therapy at the Department of Pharmacy, University of Patras, Greece in collaboration with the Department of Social and Preventive Medicine, University of Malaya, Malaysia which has already been published [ 10 , 11 ]. Considering its aim and objectives, this study focused on students’ perceptions probed by close-ended questions regarding 6 topics of interest; (1) Students’ genetic training, (2) Benefits of genetic testing on disease management, (3) PGx benefits on drug management, (4) Concerns (risks) about genetics, (5) Attitudes towards genetics’ research and testing usefulness and (6) Students’ intention to adopt genetic testing for personal use (Additional file 1 : Table S1).…”

Section: Methodsmentioning

confidence: 99%

“…Our group has an active research interest in assessing and reporting the level of awareness of pharmacy students regarding genetic testing and its application in Greece [ 8 ]. In previous surveys, we have investigated the perceptions and attitudes of medical and pharmacy health science students towards genetic testing in Southeast Asia and Southern Europe, gaining insight into their existing perceptions [ 10 , 11 ]. Evidently, it was possible to estimate the adoption level of PM in Malaysia and Greece correspondingly by pinpointing the main factors that affect genetic testing adoption and to explore the impact that cultural differences exert on technological innovation acceptance.…”

Section: Introductionmentioning

confidence: 99%

Examining key factors impact on health science students’ intentions to adopt genetic and pharmacogenomics testing: a comparative path analysis in two different healthcare settings

et al. 2022

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Background There is an increasing interest worldwide in investigating healthcare stakeholders’ perceptions and intentions to adopt pharmacogenomics (PGx) into clinical practice. However, the existing inquiries based on well-established theories and models that interpret their intentions to implement PGx are scarce. This study is the first that examines the impact of selected factors on health science students’ intention to adopt genetic testing applications using the technology acceptance model while it compares two different cultural groups: Greeks (Europe; Christian) and Malays (Asia; Muslim). Results Malay students were more persuaded about benefits of genomics for drug management compared to their Greek counterparts. However, participants from both countries appear to be particularly convinced about the benefits of genomics on disease management. Moreover, students from both countries considered the potential misuse of genetic information by corporate or government bodies as their most important concern; Greek students appeared to be considerably less worried than Malay about other probable hazards such as the deficient protection of privacy and confidentiality, which could be attributed to their religious background. Participants from both samples expressed very positive attitudes towards genetic research and testing and their favourable intentions to adopt genetic testing for personal use. Exploratory factors analysis and path analysis yielded quite similar results for both samples. Path analysis revealed that the factors of attitudes, concerns, drug management benefits and disease management benefits significantly influenced students’ intentions to adopt genetic testing for personal use, with attitudes being the most inspirational factor with rather high impact, while training did not seem to affect participant’s intentions. The squared multiple correlation of both models was quite satisfactory reaching to 0.55 for the Malaysian sample. Conclusion Similarities in the results of the two groups along with the relevant validity and reliability tests indicate that the proposed model is a good fit for future studies to interpret stakeholders’ intentions to adopt genetic testing. Therefore, it can provide a promising and reliable basis for future model development to explain the relationships between intentions to adopt genetic testing and its predictors.

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What Do Students in Pharmacy and Medicine Think About Pharmacogenomics and Personalized Medicine Education? Awareness, Attitudes, and Perceptions in Malaysian Health Sciences

Cited by 13 publications

References 16 publications

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-Sectional Survey in Lagos, Nigeria

Preparedness of Nigerian Medical Students for an Era of Precision Medicine – A Cross-Sectional Survey in Lagos, Nigeria

Knowledge, Attitude and Perception of Pharmacy Students towards Pharmacogenomics and Genetics: An Observational Study from King Saud University

Examining key factors impact on health science students’ intentions to adopt genetic and pharmacogenomics testing: a comparative path analysis in two different healthcare settings

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