What do patients and oncologists think about the evaluation and management of cancer-related anorexia-cachexia? The Quasar_SEOM study

Escobar, Yolanda; Ramchandani, Avinash; Salgado, Mercedes; Trujillo, Oscar Alfredo Castillo; Castro, Eva Martínez de; Corcuera, I. Diaz de; Vera, Ruth; Lacalle, A.; Torres, Irene; Segura, Pedro Pérez; Hierro, Cinta; Prado, Diego Soto de; Cotes, Almudena; Zafra, Gema Marín; Fabregat, Raquel Marse; Virizuela, Juan Antonio; Villa, José Carlos; Borrega, Pablo; Jiménez‐Fonseca, Paula

doi:10.1007/s12094-023-03212-7

Cited by 2 publications

(1 citation statement)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is no consensus as to how to perform screening and what cut-off points are required to undertake assessment [22].…”

Section: Diagnosismentioning

confidence: 99%

SEOM clinical guidelines for cancer anorexia-cachexia syndrome (2023)

Soria Rivas,

Escobar Álvarez,

Blasco Cordellat

et al. 2024

Clin Transl Oncol

View full text Add to dashboard Cite

Cancer-related anorexia-cachexia syndrome (CACS) is a debilitating condition afflicting up to 80% of advanced-stage cancer patients. Characterized by progressive weight loss, muscle wasting, and metabolic abnormalities, CACS significantly compromises patients’ quality of life and treatment outcomes. This comprehensive review navigates through its intricate physiopathology, elucidating its stages and diagnostic methodologies. CACS manifests in three distinct stages: pre-cachexia, established cachexia, and refractory cachexia. Early detection is pivotal for effective intervention and is facilitated by screening tools, complemented by nutritional assessments and professional evaluations. The diagnostic process unravels the complex interplay of metabolic dysregulation and tumor-induced factors contributing to CACS. Management strategies, tailored to individual patient profiles, encompass a spectrum of nutritional interventions. These include dietary counseling, oral nutritional supplements, and, when necessary, enteral nutrition and a judicious use of parenteral nutrition. Specific recommendations for caloric intake, protein requirements, and essential nutrients address the unique challenges posed by CACS. While pharmacological agents like megestrol acetate may be considered, their use requires careful evaluation of potential risks. At its core, this review underscores the imperative for a holistic and personalized approach to managing CACS, integrating nutritional interventions and pharmacological strategies based on a nuanced understanding of patient’s condition.

show abstract

“…There is no consensus as to how to perform screening and what cut-off points are required to undertake assessment [22].…”

Section: Diagnosismentioning

confidence: 99%