What Do Glaucomatous Visual Fields Really Look Like in Fine-Grid Computerized Profile Perimetry?

Stürmer, Jörg

doi:10.1159/000411291

Cited by 14 publications

(5 citation statements)

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“…In addition, the degree of intertest variability has been found to correlate with the degree of sensitivity loss 22. Our results confirm that a similar correlation exists between intertest variability and sensitivity loss in high spatial resolution perimetry, as has been suggested by other workers 1. To date, the high intertest variability, and consequently low repeatability, in areas of glaucomatous sensitivity loss has been a significant limitation to the usefulness of high spatial resolution perimetry.…”

Section: Discussionsupporting

confidence: 89%

“…Another recognised problem of high spatial resolution perimetry has been a high intratest variability, with a corresponding poor repeatability of the threshold measurements 1. We have developed a technique to perform high spatial resolution perimetry using a Humphrey perimeter to generate a fine matrix map (FMM) of a specified region of the visual field within an acceptable test time.…”

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confidence: 99%

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High spatial resolution automated perimetry in glaucoma

Westcott

McNaught

Crabb

et al. 1997

British Journal of Ophthalmology

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Background-Automated perimetry is of fundamental importance in assessing visual function in glaucoma. A technique was evaluated to perform high spatial resolution automated perimetry to allow a more detailed assessment of the luminance sensitivity in selected regions of the visual field than is possible with conventional perimetry. Method-High spatial resolution perimetry was performed using a Humphrey automated perimeter by measuring luminance sensitivity across a 9 by 9 degree custom grid of 100 test locations with a separation between adjacent locations of 1 degree. Quantitative analysis of the raw and Gaussian filtered thresholds was performed to assess the repeatability of the technique in normals, glaucoma suspects, and glaucoma patients. Results-The testing protocol was well tolerated by all subjects. High spatial resolution perimetry in glaucomatous eyes demonstrated fine luminance sensitivity loss not suspected with conventional perimetry. High spatial resolution perimetry also demonstrated reproducible areas of sensitivity loss in some glaucomatous eyes in areas of the visual field which appear normal with conventional programmes. The repeatability of the technique correlated with mean threshold sensitivity and was substantially improved to clinically acceptable levels by Gaussian filtering the thresholds. Conclusion-This technique of high spatial resolution perimetry allows the practical assessment of selected regions of the visual field at higher resolution than conventional perimetry, and may be clinically useful in glaucoma. (Br J Ophthalmol 1997;81:452-459)

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Section: Discussionsupporting

confidence: 89%

mentioning

confidence: 99%

High spatial resolution automated perimetry in glaucoma

Westcott

McNaught

Crabb

et al. 1997

British Journal of Ophthalmology

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“…In order to maximize the benefit of diagnostic information, optimal test conditions are desirable, including optimized test point density, spatial distribution and number of test point locations. Approaches such as fine grid perimetry or interlocking grids such as the 30-1 and 30-2 tests used in Humphrey perimetry or the 31 and the 32 programs applied with the Octopus instrument do indeed show high spatial resolution, but they are considerably disadvantageous in terms of expenditure of time (Stu¨rmer et al 1984;Stu¨rmer 1985;Gloor & Gloor 1986). The rectangular test point arrangements of the classic grids, which have been used predominantly so far, give inadequate consideration to the pattern of retinal receptor and ganglion cell distribution (Weber & Kosel 1986;Schiefer et al 2003a).…”

Section: Introductionmentioning

confidence: 99%

Age‐dependent normative values for differential luminance sensitivity in automated static perimetry using the Octopus 101

Hermann

Paetzold

Vonthein

et al. 2008

Acta Ophthalmologica

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ABSTRACT.Purpose: To determine age-dependent normative differential threshold values for the Octopus 101 instrument and to create a smooth mathematical model characterizing the age-dependency and asymmetry of the hill of vision. Methods: Static automated perimetry within the central 30°visual field (VF) was conducted with the Octopus 101 (background luminance 10 cd ⁄ m 2 ) in 81 eyes of 81 ophthalmologically healthy subjects (11-12 per decade of age) aged 10-79 years. A 4-2-2 staircase strategy with three reversals was run. The test point grid consisted of 68 concentrically arranged points with test point condensation towards the VF centre, representing the approximately rotation-symmetrical 30°hill of vision. Thresholds of differential luminance sensitivity (DLS) were estimated by the maximum likelihood method. A smooth mathematical model was fitted to the normative data. Results: The model fit was satisfactory (r 2 = 0.74). Covariables were: age, eccentricity, angle and subject. Total random standard deviation (SD) was 1.75 dB. The residual SD exceeded 1.75 dB in the border region, was 1.5 dB within the centre and fell below 1.25 dB in a ring around the centre. Average thresholds of DLS varied with age quadratically. It is close to constant for the 10-40-year-old age group and declines ever more steeply thereafter. The effect of age on DLS in the VF increased with eccentricity. The greatest drop was located in the peripheral superior hemifield: at 25°eccentricity the superior DLS was estimated to be 5.5 dB higher in 10-year-olds than in 75-year-olds. Conclusions: This new smooth model allows for the prediction of age-related normal threshold values for any stimulus location within the 30°VF and thus for the calculation of global and local measures of defect such as mean defects or p-values for any type of stimulus.

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“…In conclusion, through computer simulation, it has been discovered that the improvement in precision and accuracy around scotoma borders seen in the GOANNA framework translates to more accurate classification of progressing fields compared with ZEST, especially in the early stages of glaucomatous progression. There have been a number of studies which report that high resolution grids can detect glaucomatous defects earlier than conventional 6° grids, especially when defects are of a higher resolution at which conventional perimetry samples . These findings suggest that the spatial resolution of conventional perimetry is not adequate to accurately detect early glaucomatous changes in the visual field.…”

Section: Discussionmentioning

confidence: 99%