What Are We Missing From Asymmetric Relationship Between the Retinal Nerve Fiber Layer Thickness Profiles and Sphenoid Sinus Volume?

Abstract

Purpose/Aim of the Study: Detailed analysis of retinal structure such as the retinal nerve fiber layer can be performed by spectral-domain optical coherence tomography (OCT). There are no published studies concerning a relationship between retinal nerve fiber layer and human sphenoid sinus volumes. We investigated this relationship. Material and Methods: Spectral-domain OCT. The peripapillary retinal nerve fiber layer (RNFL) thickness and sphenoid sinus volume estimation of both sides of sex-matched patients were retrospectively analyzed. Results: The mean RNFL thicknesses at the left side (91.8 μm) were significantly smaller than the right side (94.5 μm) (P = 0.040). However, the mean left sinus volume (44.5 cm3) is larger than the right side, (34.5 mm3) (P < 0.005). Left and right differences of both parameters are statistically significant (P < 0.05). Conclusion: There is a negative correlation between mean RNFL thicknesses and mean sinus volumes. To our knowledge, this article is the first report demonstrating the asymmetry relationship between RNFL and sphenoid sinus volumes.

Olfactory bulbectomy leads to prolonged induction phase of sevoflurane anesthesia in rats

“…Certain anatomical structures in the skull base called for detailed study because of their functional importance, 23 24 such as OB which is a paired oval-shaped neural structure of the anterior cranium base. The cribriform plate provides a passage between the OB and the brain.…”