What are the pharmacotherapeutic options for adjustment disorder?

Hoffman, Jacob; Stein, Dan J.

doi:10.1080/14656566.2022.2033209

Cited by 4 publications

(2 citation statements)

References 17 publications

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“…While the clinical condition of AD often overlaps with depression and anxiety disorders, leading to the frequent prescription of SSRIs, 43 as observed in our sample, some authors recommend caution in unnecessary drug use for mild cases, considering that AD tends to improve naturally after the removal of stressors 41 . Regrettably, the existing literature still lacks definitive guidance on the treatment of AD 41,44,45 . The current study also highlights this gap in AD management.…”

Section: Discussionmentioning

confidence: 58%

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Adjustment disorder and its risk factors during the solid organ pre‐transplant period for children: A retrospective analysis of the last 10 years

Kaba,

Sarı,

Taner

2023

Pediatric Transplantation

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BackgroundAdjustment disorder (AD) in individuals suffering from end‐stage organ failure can negatively impact treatment adherence and overall quality of life. Previous research focusing on adults has suggested that AD might serve as a precursor to major mental disorders. However, although it is frequently used as a diagnosis in consultation‐liaison psychiatry, our understanding of AD in pediatric transplant candidates remains limited. Therefore, the objective of this study is to assess AD and identify its associated risk factors among children who are candidates for heart, kidney, and liver transplantation.MethodsData were collected retrospectively from a cohort of 155 children, aged between 6 months and 18 years (mean age 9.4), who had undergone consultations for child and adolescent psychiatry at a hospital with a transplant center within the past 10 years.ResultsThe predominant diagnosis among children assessed during the pre‐transplant period was AD (20%), with the subtype “with depressed mood” being the most commonly observed (35.5%). Organ type and length of hospital stay were identified as significant independent predictors of AD. Being a heart transplant candidate was determined as the strongest predictor of AD among children who underwent consultations with child and adolescent psychiatry within the population of transplant candidates.ConclusionsThe study found that AD was the most common diagnosis among transplant candidates who underwent psychiatric consultations. Additionally, the study identified the length of hospital stay and the type of organ needed as independent predictors of AD. Screening for AD by considering risk factors may provide an opportunity for early intervention before the occurrence of major mental disorders in transplant candidates.

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Section: Discussionmentioning

confidence: 58%

“…41 Regrettably, the existing literature still lacks definitive guidance on the treatment of AD. 41,44,45 The findings of this study should be interpreted within the context of several limitations. Firstly, our research adopts a retrospective and cross-sectional design.…”

Section: Number Of Patients (%)mentioning

confidence: 87%

Adjustment disorder and its risk factors during the solid organ pre‐transplant period for children: A retrospective analysis of the last 10 years

Kaba,

Sarı,

Taner

2023

Pediatric Transplantation

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Cardiac disease-induced trauma and stress-related disorders

Princip,

Ledermann,

Altwegg

et al. 2024

Herz

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Objective This review aims to present an updated overview of cardiac disease-induced trauma and stress-related disorders such as acute stress disorder (ASD), adjustment disorder (AjD), and posttraumatic stress disorder (PTSD). First, the prevalence of these disorders, their diagnostic criteria, and their differences from other trauma-related disorders are described. Special challenges in diagnosis and treatment are identified, with various screening tools being evaluated for symptom assessment. Additionally, the risk factors studied so far for the development of symptoms of cardiac-induced posttraumatic stress disorder and the bidirectional relationship between posttraumatic stress disorder and cardiovascular diseases are summarized. Various therapeutic interventions, including pharmacological approaches, are also discussed. Finally, various areas for future research are outlined. Background Experiencing a cardiovascular disease, particularly a life-threatening cardiac event, can potentially lead to stress-related disorders such as ASD, AjD, and cardiac disease-induced PTSD (CDI-PTSD). If left untreated, these disorders are associated with a worsening cardiac prognosis and higher mortality rates. Approaching treatment through a trauma-focused lens may be beneficial for managing CDI-PTSD and stress-related disorders. Conclusion Future research should explore treatment options for both the patients and the caregivers as well as investigate the long-term effects of trauma-focused interventions on physical and mental health outcomes.

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