West Nile Virus Antibody Titers and Total Immunoglobulin G Concentrations in Foals from Mares Vaccinated in Late Gestation

Turner, John P.; Waggoner, J. W.; Rose, Susan S.; Arns, M.J.; Hankins, Kevin; Tuttle, John R.

doi:10.1016/j.jevs.2007.11.009

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Younger animals should be excluded from immunological analyses because the presence of maternal antibodies in their systems could lead to a misinterpretation of the results. Maternal antibodies against WNV have been shown to remain detectable in the serum of horses for up to 120 days [ 166 ] and of birds for up to 9 days in passerines [ 167 ] and 42 days in domestic chicken [ 168 ]. If young animals that are old enough to have cleared maternal antibodies are seropositive, it suggests that recent transmission has occurred within a group or population, and the results may thus help identify the time period during which the virus was circulating [ 76 , 132 ].…”

Section: Serological Cross-reactions Between West Nile and Relatedmentioning

confidence: 99%

Flaviviruses in Europe: Complex Circulation Patterns and Their Consequences for the Diagnosis and Control of West Nile Disease

Beck

Jiménez‐Clavero²,

Leblond

et al. 2013

IJERPH

153

155

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In Europe, many flaviviruses are endemic (West Nile, Usutu, tick-borne encephalitis viruses) or occasionally imported (dengue, yellow fever viruses). Due to the temporal and geographical co-circulation of flaviviruses in Europe, flavivirus differentiation by diagnostic tests is crucial in the adaptation of surveillance and control efforts. Serological diagnosis of flavivirus infections is complicated by the antigenic similarities among the Flavivirus genus. Indeed, most flavivirus antibodies are directed against the highly immunogenic envelope protein, which contains both flavivirus cross-reactive and virus-specific epitopes. Serological assay results should thus be interpreted with care and confirmed by comparative neutralization tests using a panel of viruses known to circulate in Europe. However, antibody cross-reactivity could be advantageous in efforts to control emerging flaviviruses because it ensures partial cross-protection. In contrast, it might also facilitate subsequent diseases, through a phenomenon called antibody-dependent enhancement mainly described for dengue virus infections. Here, we review the serological methods commonly used in WNV diagnosis and surveillance in Europe. By examining past and current epidemiological situations in different European countries, we present the challenges involved in interpreting flavivirus serological tests and setting up appropriate surveillance programs; we also address the consequences of flavivirus circulation and vaccination for host immunity.

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Section: Serological Cross-reactions Between West Nile and Relatedmentioning

confidence: 99%

Flaviviruses in Europe: Complex Circulation Patterns and Their Consequences for the Diagnosis and Control of West Nile Disease

Beck

Jiménez‐Clavero²,

Leblond

et al. 2013

IJERPH

153

155

View full text Add to dashboard Cite

show abstract

“…In this study, foals were found to be positive for the WNV antibody on a farm where mares carry antibodies against WNV, while antibody presence was not detected for those of the other two who also showed antibody presence in mothers. It has been reported that WNV vaccination of mares in late pregnancy has a functional consequence on foal WNV titer [21]. In this study, the percentage of positive antibodies against WNV disease in the weaning foals was found to be higher than the colts.…”

Section: Discussionmentioning

confidence: 47%

Seroprevalence of West Nile Virus among Arabian Horses in Central, Eastern Anatolia, and Marmara, Turkey

Akkutay-Yoldar¹,

Tezcan-Ülger²

2018

azb

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The West Nile Virus (WNV), a mosquito-borne Flavivirus is a common infection identified in the Middle East, Europe, West Asia, Africa, Australia and the United States. The virus can cause severe illnesses and death in horses. The current study aimed to screen West Nile virus neutralizing antibodies in Arabian horse populations from breeding farms located in Central, Eastern Anatolia and Marmara by plaque reduction neutralization test (PRNT). We sampled 165 Arabian racehorses, during March-December, 2010, in three different provinces (Eskişehir, Malatya, and Bursa) in Turkey. Screening of serum samples showed that 6.6% were positive for West Nile (WN) virus-neutralizing antibodies. The obtained data demonstrate WNV is circulating in mentioned regions among racehorses and the need to carry out a surveillance program includes WNV-focused screening tests in Turkey.

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Long-term serological surveillance for West Nile and Usutu virus in horses in south-West Spain

Magallanes

Llorente²,

Ruiz‐López

et al. 2023

One Health

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West Nile Virus Antibody Titers and Total Immunoglobulin G Concentrations in Foals from Mares Vaccinated in Late Gestation

Cited by 3 publications

References 8 publications

Flaviviruses in Europe: Complex Circulation Patterns and Their Consequences for the Diagnosis and Control of West Nile Disease

Flaviviruses in Europe: Complex Circulation Patterns and Their Consequences for the Diagnosis and Control of West Nile Disease

Seroprevalence of West Nile Virus among Arabian Horses in Central, Eastern Anatolia, and Marmara, Turkey

Long-term serological surveillance for West Nile and Usutu virus in horses in south-West Spain

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