West African timbers. Part XVII. Correlation of gedunin, methyl angolensate, and andirobin

Ekong, D. E. U.; Olagbemi, E. O.

doi:10.1039/j39660000944

Cited by 4 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Andirobin-class limonoids are characterized as the cleavages of C-7/8 and C-16/17 and the formation of Δ 8,30 exocyclic double bond and δ-lactonic D ring. The chemical correlations of gedunin ( 416 ) with 556 and with methyl angolensate ( 568 ) supported the structures previously proposed for 556 and 568 . Methyl angolensate ( 568 ) was distributed widely, especially in the genus Khaya (Table ).…”

Section: Meliaceous Limonoids and Their Sourcessupporting

confidence: 80%

Meliaceous Limonoids: Chemistry and Biological Activities

2011

View full text Add to dashboard Cite

Section: Meliaceous Limonoids and Their Sourcessupporting

confidence: 80%

Meliaceous Limonoids: Chemistry and Biological Activities

2011

View full text Add to dashboard Cite

“…The furan ring at C17 in Andirobin isolated earlier 302 is replaced by γ-ethoxy butenolide in Andirolide S (680). The carbonyl at C3 in Methyl angolensate isolated previously 303 is replaced by the tigloyl group in Cipaferen N (681). Cipaferen E-G (682-684) are derived from compound (681) and differ in substitution at C2 and C3.…”

Section: 3223mentioning

confidence: 99%

Chemistry and Biology of Novel Meliaceae Limonoids

Mulani

Nandikol

Thulasiram

2022

Preprint

View full text Add to dashboard Cite

Nature has bestowed us with abundant bioactive/drug molecules for various uses in our everyday life. One such group of plant specialized molecules is limonoids, which are structurally characterized as 4,4,8-trimethyl-17-furanyl steroidal skeleton. Limonoids are well known for their various biological activities such as potent anti-feedent, anti-cancer, anti-inflammatory, insecticidal, anti-diabetic, anti-viral, anti-microbial etc. These tetranortriterpenes are highly oxygenated and structurally diversified molecules majorly found in Meliaceae and Rutaceae and less frequently in the Cneoraceae families in the plant kingdom. Many of these plants have been used in traditional medicine from ages. One of the well-known limonoid, azadirachtin A is highly valued and widely popular for its outstanding insecticidal properties. Till date, nearly 2500 limonoids with over 35 unique carbon frameworks have been observed. In recent times, these molecules have dig a great interest among researchers due to their myriad biological properties. With the advancement of analytical techniques, the limonoid research is aced to explore more different molecules from their sources. In our review we cover all the Meliaceous limonoids isolated during July 2010 to Dec 2020. We found over 1502 new limonoids, which are reported from various Meliaceae plants after Jun 2010. We have classified them based on their skeletal structure rearrangements and functional groups into various classes such as protolimonoids, Apoprotolionoid, Azadirone, Vilasinin, Cedrelone, Havanensin, Trichilin, Nimbin, Salannin, Azadirachtin, Nimbolidin, Nimbolinin, Obacunol, Evodulone, Trijugin, Cipadesin, Andirobin, Mexicanolide, Phragmalin, Khayanolide, Preieurianin, Aphanamixoid, Nor Limonoid and N-containing derivatives. Further we have discussed their biological activities in detail.

show abstract

Terpenes (including Steroids)

Klyne¹,

Buckingham²

1974

Atlas of Stereochemistry

View full text Add to dashboard Cite

West African timbers. Part XVII. Correlation of gedunin, methyl angolensate, and andirobin

Cited by 4 publications

References 0 publications

Meliaceous Limonoids: Chemistry and Biological Activities

Meliaceous Limonoids: Chemistry and Biological Activities

Chemistry and Biology of Novel Meliaceae Limonoids

Terpenes (including Steroids)

Contact Info

Product

Resources

About