Wernicke's encephalopathy in a non‐alcoholic patient with a normal blood thiamine level

Davies, Shakiela Khanam; Joshua, Fredrick; Zagami, Alessandro S

doi:10.5694/j.1326-5377.2011.tb03068.x

Cited by 35 publications

(13 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The sensitivity and specificity of serum thiamine level in symptomatic patients is unclear, as the blood level may not reflect the brain thiamine level. A normal blood thiamine level, as in our patient, does not exclude the possibility of WE with MRI findings [5]. MRI is more sensitive than CT in WE [6].…”

Section: To the Editormentioning

confidence: 83%

Wernicke’s Encephalopathy in a Child with Acute Lymphoblastic Leukemia

Kizilocak

Özdemir²,

Dikme³

et al. 2017

Tjh

View full text Add to dashboard Cite

Section: To the Editormentioning

confidence: 83%

Wernicke’s Encephalopathy in a Child with Acute Lymphoblastic Leukemia

Kizilocak

Özdemir²,

Dikme³

et al. 2017

Tjh

View full text Add to dashboard Cite

“…Diagnostic workup includes laboratory studies such as serum thiamine levels and red blood cell (RBC) transketolase activity. Usually, the levels are low but can be normal [ 16 ]. When a diagnosis of WE is suspected, immediate thiamine replacement takes precedence over laboratory findings.…”

Section: Discussionmentioning

confidence: 99%

A Case of Wernicke’s Encephalopathy in a Pregnant Woman With a History of Sleeve Gastrectomy

Kandlakunta¹,

Gurala²,

Philipose³

et al. 2020

Cureus

View full text Add to dashboard Cite

Wernicke’s encephalopathy (WE) is a neurological complication of thiamine deficiency characterized by a triad of acute confusion, ataxia, and ophthalmoplegia. Even though it is most common in chronic alcoholism, an increase in prevalence has been reported recently due to the increased popularity of bariatric surgeries. WE is a known neurological complication after gastric bypass surgery but rarely reported after sleeve gastrectomy. We present a unique case of WE in pregnant women four months after sleeve gastrectomy.

show abstract

“…Whole blood thiamine is the preferred assay, 39 but thiamine levels are often normal in WE because blood levels do not adequately reflect brain thiamine levels. [40][41] Blood samples should be drawn before thiamine supplementation is provided, as laboratory abnormalities quickly return to normal with treatment. 42 and at the borders of the third and fourth ventricles.…”

Section: Discussionmentioning

confidence: 99%

Wernicke Encephalopathy Owing to Vitamin Nonadherence Following Bariatric Surgery

Killeen¹,

O’Rourke²,

Trobe³

2018

Michigan Journal of Medicine

View full text Add to dashboard Cite

Introduction and Objective Wernicke encephalopathy (WE) is increasingly recognized as a complication of bariatric surgery precipitated by nonadherence to vitamin supplementation in the setting of presurgical hypovitaminosis, nausea, vomiting, gastrointestinal dysmotility, and the high cost of vitamins. Anticipation of this phenomenon allows prompt diagnosis and treatment, which can prevent serious neurologic morbidity and even death. Case Presentation We present a patient with prominent neuro-ophthalmic manifestations of Wernicke encephalopathy from medication nonadherence owing to a combination of factors: the high cost of vitamin supplements, nausea, and depression. Discussion Wernicke encephalopathy after bariatric surgery is likely to become more common as these procedures increase in frequency. Physicians should recognize the factors that lead to medication nonadherence in this context and anticipate the development of Wernicke encephalopathy, as early recognition is critical to prevent enduring neurologic deficits. Conclusion Anticipation of this phenomenon allows prompt diagnosis and treatment, which can prevent serious neurologic morbidity and even death.

show abstract

Wernicke's encephalopathy in a non‐alcoholic patient with a normal blood thiamine level

Cited by 35 publications

References 8 publications

Wernicke’s Encephalopathy in a Child with Acute Lymphoblastic Leukemia

Wernicke’s Encephalopathy in a Child with Acute Lymphoblastic Leukemia

A Case of Wernicke’s Encephalopathy in a Pregnant Woman With a History of Sleeve Gastrectomy

Wernicke Encephalopathy Owing to Vitamin Nonadherence Following Bariatric Surgery

Contact Info

Product

Resources

About