We find necessary and sufficient conditions for the validity of weighted Rellich inequalities in L p , 1 ≤ p ≤ ∞, for functions in bounded domains vanishing at the boundary. General operators like L = ∆ + c x |x| 2 · ∇ − b |x| 2 are considered. Critical cases and remainder terms are also investigated.Mathematics subject classification (2010): 26D10, 35PXX, 47F05.