Weight management in adults with intellectual and developmental disabilities: A randomized controlled trial of two dietary approaches

Ptomey, Lauren T.; Saunders, Richard; Saunders, Muriel D.; Washburn, Richard A.; Mayo, Matthew S.; Sullivan, Debra K.; Gibson, Cheryl; Goetz, Jeannine; Honas, Jeff J.; Willis, Erik A.; Danón, J; Krebill, Ron; Donnelly, Joseph E.

doi:10.1111/jar.12348

Cited by 40 publications

(54 citation statements)

References 70 publications

(143 reference statements)

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“…Fourteen studies were conducted in people who were overweight but with no specific clinical condition, five in people with type 2 diabetes, two in participants with metabolic syndrome or impaired glucose regulation, one in men with type 2 diabetes and erectile dysfunction, and one in adults with developmental disabilities and obesity …”

Section: Resultsmentioning

confidence: 99%

“…In 15 studies (65%), the MR used consisted of specially formulated shakes, soups, or bars . In four studies (17%), the MR consisted of prepackaged portion‐controlled meals which participants reconstituted or cooked at home, and in four studies (17%), the MR was a combination of prepackaged portion‐controlled meals and specially formulated shakes, soups, or bars …”

Section: Resultsmentioning

confidence: 99%

“…Twelve studies also included a second MR phase for continued weight loss or weight maintenance where continued use of MR was recommended, generally at a reduced level. The median duration of this phase was 42 weeks [IQR 30 to 52 weeks] …”

Section: Resultsmentioning

confidence: 99%

“…During the weight loss phase, 13 studies advised participants to replace two eating occasions each day with a MR . One study advised participants to replace one eating occasion, and one, two, and four studies advised participants to replace three, four, or five eating occasions (meals or snacks) with one MR, respectively. Two studies (four intervention arms) did not specify the number of MR products participants were advised to consume, but rather recommended that participants replace a proportion of their daily energy intake with the MR products …”

Section: Resultsmentioning

confidence: 99%

“…In 15 studies, in addition to the MR diet, participants also received support for weight loss during the active intervention. This support consisted of 12 sessions [IQR 7 to 19] over 24 weeks, ranging from 12 to 52 weeks [IQR 12 to 52 weeks] (MR diet + support) . In two studies (four intervention arms), an enhanced level of support was offered to the MR group (73 sessions [IQR 57.5 to 88.5 sessions] over 78 weeks [IQR 65 to 91 weeks]) compared with the support provided to the control group which consisted of two sessions [IQR 2 to 2] over 78 weeks [IQR 65 to 91 weeks]) (MR diet + enhanced support) …”

Section: Resultsmentioning

confidence: 99%

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A systematic review and meta‐analysis of the effectiveness of meal replacements for weight loss

et al. 2019

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SummaryMeal replacements (MR) are generally not recommended in clinical guidelines for the management of obesity. The aim of this review is to provide an up‐to‐date systematic evaluation of the effect of weight loss interventions incorporating MR compared with alternative interventions on weight change at 1 year in adults with overweight or obesity. Six electronic databases were searched from inception to the end of August 2018 for randomized controlled trials comparing the effect of MR with interventions that did not include MR on weight at 1 year. We excluded studies using diets providing <3347 kJ/(800 kcal)/day and those which used total diet replacement (TDR) from this review. Risk of bias was assessed using the Cochrane risk of bias tool. Twenty‐three studies with 7884 adult participants were included. Six out of 23 studies were judged at low risk of bias across all domains, and 5/23 studies were judged at high risk of bias in at least one domain. Studies with similar intervention and comparators were grouped into five comparisons for analysis. Mean weight change at 1 year favoured the MR group relative to the control group in each comparison. In those comparisons where we conducted meta‐analysis, in people assigned to a diet incorporating MR, mean difference was −1.44 kg (−2.48 to −0.39 kg; I 2 = 38%) compared with alternative kinds of diets. In those assigned to a MR diet along with support, mean difference was −2.22 kg (−3.99 to −0.45, I 2 = 81%) compared with other diets with support and −3.87 kg (−7.34 to −0.40; I 2 = 60%) compared with other kinds of diet without support. In those assigned a MR diet with an enhanced level of support, mean difference was −6.13 kg (−7.35 to −4.91, I 2 = 19%) compared with alternative diets and regular support. Programmes incorporating meal replacements led to greater weight loss at 1 year than comparator weight loss programmes and should be considered as a valid option for management of overweight and obesity in community and health care settings.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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A systematic review and meta‐analysis of the effectiveness of meal replacements for weight loss

et al. 2019

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Factors in Weight Management: A Research Story

Saunders

Donnelly

et al. 2019

Handbook of Intellectual Disabilities

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A Randomized Controlled Trial of a Telehealth Family-Delivered Mindfulness-Based Health Wellness (MBHW) Program for Self-Management of Weight by Adolescents with Intellectual and Developmental Disabilities

Myers

Medvedev

et al. 2023

Mindfulness

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Objectives The prevalence of overweight and obesity is high in adolescents with intellectual and developmental disabilities (IDD), and the availability of and engagement in self-determined health and wellness programs is limited. The objective of the present study was to assess the effectiveness of the Mindfulness-Based Health Wellness (MBHW) program of using telehealth to enable families to teach a field-tested lifestyle change program to their adolescents with IDD. The program encouraged the adolescents to self-determine the parameters of the program that they could use to self-manage their weight through a lifestyle change process. Method Eighty adolescents were randomized into experimental (n = 42) and control (n = 38) groups. The experimental group engaged in the MBHW program as taught by their families, and the control group engaged in treatment as usual (TAU) in a randomized controlled trial. Adolescents in the experimental group self-determined the parameters of each of the five components of the MBHW program and engaged in self-paced weight reduction using a changing-criterion design. Results All 42 adolescents in the experimental group reached their target weights and, on average, reduced their weight by 38 lbs. The 38 adolescents in the control group reduced their weight by an average of 3.47 lbs. by the end of the study. There was a large statistically significant effect of the MBHW program on reduction of both weight and body mass index (BMI) for adolescents in the experimental group. Family members and adolescents rated the MBHW program as having high social validity, and the intervention was delivered with a high degree of fidelity. Conclusions Families can support adolescents with IDD to use the MBHW program to effectively self-manage their weight through a lifestyle change program. Future research should use an active control group, assess maintenance of weight loss across settings and time, use relative fat mass (RFM) for estimating body fat percentage, and evaluate the impact of consuming highly processed foods on weight loss interventions.

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Weight management in adults with intellectual and developmental disabilities: A randomized controlled trial of two dietary approaches

Abstract: The eSLD and CD provided clinically meaningful weight loss over 18 months in adults with intellectual and developmental disabilities.

Cited by 40 publications

References 70 publications

A systematic review and meta‐analysis of the effectiveness of meal replacements for weight loss

A systematic review and meta‐analysis of the effectiveness of meal replacements for weight loss

Factors in Weight Management: A Research Story

A Randomized Controlled Trial of a Telehealth Family-Delivered Mindfulness-Based Health Wellness (MBHW) Program for Self-Management of Weight by Adolescents with Intellectual and Developmental Disabilities

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