Weight loss and metabolic improvements in obese patients undergoing gastric banding and gastric banded plication: A comparison

Wang, Weu; Fann, Cathy S.J.; Yang, Shwu Huey; Chen, Hsin Hung; Chen, Chih-Yen

doi:10.1016/j.nut.2018.05.024

Cited by 12 publications

(11 citation statements)

References 28 publications

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“…Others report better outcomes after 36 months in a study of 290 patients, with a significant decrease in blood pressure, glucose, and cholesterol levels [10]. However, the study population was younger (20-55 years old), had lower initial BMI levels, and lower rates of comorbidities [10]. Similar findings were reported by Steffen et al in a 7-year prospective study on 388 patients undergoing LAGB [11].…”

Section: Discussionsupporting

confidence: 62%

“…2 Younger patients lost more weight through the follow-up period, with statistically significant results obtained 2 years after surgery metabolic parameters. Others report better outcomes after 36 months in a study of 290 patients, with a significant decrease in blood pressure, glucose, and cholesterol levels [10]. However, the study population was younger (20-55 years old), had lower initial BMI levels, and lower rates of comorbidities [10].…”

Section: Discussionmentioning

confidence: 97%

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Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?

et al. 2020

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Background Obesity is a chronic relapsing-remitting disease and a global pandemic, being associated with multiple comorbidities. Laparoscopic adjustable gastric banding (LAGB) is one of the safest surgical procedures used for the treatment of obesity, and even though its popularity has been decreasing over time, it still remains an option for a certain group of patients, producing considerable weight loss and improvement in obesity-associated comorbidities. Methods The aim of this study was to evaluate the impact of weight loss following LAGB on obesity-associated comorbidities, and to identify factors that could predict better response to surgery, and patient sub-groups exhibiting greatest benefit. A total of 99 severely obese patients (81.2% women, mean age 44.19 ± 10.94 years, mean body mass index (BMI) 51.84 ± 8.77 kg/m2) underwent LAGB in a single institution. Results obtained 1, 2, and 5 years postoperatively were compared with the pre-operative values using SPPS software version 20. Results A significant drop in BMI was recorded throughout the follow-up period, as well as in A1c and triglycerides, with greatest improvement seen 2 years after surgery (51.8 ± 8.7 kg/m2 vs 42.3 ± 9.2 kg/m2, p < 0.05, 55.5 ± 19.1 mmol/mol vs 45.8 ± 13.7 mmol/mol, p < 0.05, and 2.2 ± 1.7 mmol/l vs 1.5 ± 0.6 mmol/l). Better outcomes were seen in younger patients, with lower duration of diabetes before surgery, and lower pre-operative systolic blood pressure. Conclusions Younger age, lower degree of obesity, and lower severity of comorbidities at the time of surgery can be important predictors of successful weight loss, making this group of patients the ideal candidates for LAGB.

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 97%

Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?

et al. 2020

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“…Currently, bariatric surgery is considered a promising treatment strategy because of its long-term benefits for morbidly obese patients. These benefits include the following: Sustainable body weight loss; improvement in comorbidities; reduction in medicine use; and improvement in patients’ quality of life[ 1 - 8 ]. However, post-bariatric surgery anemia, which mainly results from micronutrient deficiencies, is recognized as the most common adverse effect[ 3 - 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…The incidence of obesity has increased rapidly and has tripled over the past decades[ 1 ], significantly threatening public health. Bariatric surgery has been shown to be the most effective long-term treatment for morbidly obese patients[ 1 - 4 ] considering that this surgery results in significant and sustainable weight loss and improves comorbidities, long-term mortality, and patients’ quality of life[ 1 - 8 ]. Although bariatric surgery is considered safe and has beneficial effects, the development of anemia after bariatric surgery remains a concern.…”

Section: Introductionmentioning

confidence: 99%

Risk of anemia in morbidly obese patients after bariatric surgery in Taiwan

Wang

Hsieh²,

Chen

2020

WJD

Self Cite

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BACKGROUND Bariatric surgery is one of most effective long-term treatments for morbid obesity. However, post-bariatric surgery anemia is identified as a common adverse effect and remains a challenge nowadays. AIM To estimate the risk of post-bariatric surgery anemia and to stratify the association between age, gender, and types of surgery. METHODS This study is a population-based cohort study. We conducted this nationwide study using claims data from National Health Insurance Research Database in Taiwan. There were 4373 morbidly obese patients in this study cohort. RESULTS Among patients who were diagnosed with morbid obesity, 2864 received bariatric surgery. All obesity-associated comorbidities decreased in the surgical group. Increasing risk of post-bariatric surgery anemia among obese patients was found by Cox proportional hazards regression [adjusted hazard ratio (HR): 2.36]. Also, we found significantly increasing cumulative incidence rate of anemia among patients receiving bariatric surgery by log-rank test. After adjusting for age and gender, the increasing incidence of post-bariatric surgery anemia was found among women (adjusted HR: 2.48), patients in the 20–29-year-old group (adjusted HR: 3.83), and patients in the 30-64-year-old group (adjusted HR: 2.37). Moreover, malabsorptive and restrictive procedures had significantly higher adjusted HRs, 3.18 and 1.55, respectively. CONCLUSION Bariatric surgery give rise to anemia risk among obese patients, specifically in women, young- and middle-aged patients, and patients undergoing malabsorptive procedures in our population-based cohort study in Taiwan.

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“…Evidence on the importance of the stomach in improving glucose control is abundant, although it is still lacking in clear definition. A recent study reported that gastric banding and gastric banded plication, procedures that modified only the stomach, resulted in excellent weight loss and improvements in metabolic parameters [17]. As the stomach is an organ for digestion [18], bypassing the majority of the stomach might result in expedited undigested nutrients to the intestine, which is crucial for initiating the hindgut theory [19].…”

Section: Discussionmentioning

confidence: 99%

Short-Term Results Suggest That Sleeved Stomach without Resection Is as Effective as Sleeve Gastrectomy in Improving Glucose Control in Type 2 Diabetes Mellitus Sprague-Dawley Rat Model

Widjaja

Yao

Shao

et al. 2020

BioMed Research International

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Background. Although sleeve gastrectomy results in good weight loss and metabolic improvements, it is an irreversible procedure. Therefore, we attempted to assess the possibility of creating a sleeved stomach without resection. Material and Methods. A total of 22 male Sprague-Dawley rats with type 2 diabetes were randomly assigned into 3 different groups: (1) sleeve gastroplasty with gastric remnant-jejunal anastomosis (SGP, n=8); (2) sleeve gastrectomy (SG, n=8); and (3) SHAM (n=6). Body weight, food intake, fasting blood glucose (FBG), hormonal analysis, and oral glucose tolerance test (OGTT) were performed and measured preoperatively and postoperatively. Results. During the postoperative period, SGP and SG showed significantly lower food intake and body weight when compared with the preoperative levels, respectively (p value < 0.05). Postoperatively, SGP and SG showed improvements in FBG and glucose tolerance levels compared to their respective preoperative levels (p<0.05). FBG and glucose tolerance levels did not differ between SGP and SG postoperatively. SG resulted in a reduction in fasting ghrelin levels when compared with the preoperative level (p<0.05). Fasting insulin levels did not differ preoperatively and postoperatively among all groups. Postoperatively, fasting GLP-1 levels were higher in SGP and SG when compared with the preoperative levels, but no statistical significance was observed. Compared preoperatively, the SGP and SG procedures resulted in a decline in HOMA-IR at postoperative 6th week (p<0.05). Conclusion. Our animal experiment suggested that at least in the short term, sleeved stomach without resection resulted in similar weight loss and improved glucose control effects compared to sleeve gastrectomy.

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Weight loss and metabolic improvements in obese patients undergoing gastric banding and gastric banded plication: A comparison

Cited by 12 publications

References 28 publications

Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?

Laparoscopic Adjustable Gastric Banding—Should a Second Chance Be Given?

Risk of anemia in morbidly obese patients after bariatric surgery in Taiwan

Short-Term Results Suggest That Sleeved Stomach without Resection Is as Effective as Sleeve Gastrectomy in Improving Glucose Control in Type 2 Diabetes Mellitus Sprague-Dawley Rat Model

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