Weight loss and improvements in fatigue in systemic lupus erythematosus: a controlled trial of a low glycaemic index diet versus a calorie restricted diet in patients treated with corticosteroids

Davies, Rachel J.; Lomer, Miranda; Yeo, Seung Geun; Avloniti, K.; Sangle, SR; D’Cruz, David

doi:10.1177/0961203312436854

Cited by 61 publications

(94 citation statements)

References 28 publications

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“…A dietary intervention study of stable SLE patients on low-dose prednisone suggests significant weight loss over a 6-week period can achieve clinical improvement [8]. However, failure to adhere to long-term diet regimens and difficulty maintaining weight loss (especially in those with mobility issues) are potential pitfalls to this approach and suggest a potential role for bariatric surgery in morbidly obese lupus patients.…”

Section: Discussionmentioning

confidence: 97%

“…Specifically, an increased risk of perioperative morbidity and 30-day mortality after major surgery in SLE patients has been reported [5][6][7]. Weight loss through lifestyle and dietary modification has been shown to improve the clinical manifestations of lupus [8]. However, the effect of surgical weight loss on SLE disease activity and the perioperative morbidity/mortality of bariatric surgery in this population remains unknown.…”

mentioning

confidence: 97%

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Bariatric surgery outcomes in patients with systemic lupus erythematosus

Corcelles

Daigle

Talamas

et al. 2015

Surgery for Obesity and Related Diseases

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Section: Discussionmentioning

confidence: 97%

mentioning

confidence: 97%

Bariatric surgery outcomes in patients with systemic lupus erythematosus

Corcelles

Daigle

Talamas

et al. 2015

Surgery for Obesity and Related Diseases

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“…Shah et al 13 used a 12 week culturally sensitive, behaviorally focused diet intervention to modify CVD risk factors in 17 Hispanic-American and African-American women with SLE and found significant reductions in total cholesterol, low density lipoprotein (LDL) levels, triglycerides, and weight. In a 6-week study, Davies et al 14 evaluated the use of a low glycemic index diet compared to a traditional low calorie diet on weight loss, cardiovascular risk, disease activity, and fatigue in 23 female SLE patients on prednisone. There were no changes in CVD biomarkers but the researchers found significant weight loss achieved by subjects in both groups (p < 0.01).In contrast to the previous studies, our study was the only one to use patient-centered methods and tailored the nutrition intervention to patients’ stage of change and barriers.…”

Section: Discussionmentioning

confidence: 99%

Short-term patient-centered nutrition counseling impacts weight and nutrient intake in patients with systemic lupus erythematosus

Everett

Wolf

Contento

et al. 2015

Lupus

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Background Patients with systemic lupus erythematosus (SLE) are at risk for cardiovascular disease (CVD) due to increased prevalence of risks factors. Objective To evaluate the effect of patient-centered nutrition counseling on changes in nutrient, anthropometric, and lipids in SLE patients enrolled in a CVD prevention counseling program (CVD PCP). Methods From March 2009 to June 2011, a subgroup of SLE patients enrolled in our CVD PCP were referred for nutrition counseling. A primary analysis evaluated the 6-month changes in nutrient intake, weight, body mass index (BMI), waist circumference, and lipid levels. A secondary analysis compared the same measurements between the nutrition counseling patients and patients who were referred but did not attend. Results Of 71 referrals, 41 (58%) attended nutrition counseling (female: 88%, African American/Hispanic: 73%, mean age of 40.7 ± 12.6 years, and mean disease duration of 12.2 ± 8.2 years). Over a 6-month period, nutritional counseling patients: a) reduced sodium intake (p = 0.006), total calories (p = 0.07), percent calories from fat (p = 0.011) and saturated fat (p = 0.068); b) had decreased weight (−1.64 kg, p = 0.025); and c) were more likely to report increases in fruits and vegetables (p < 0.001), a high fiber diet (p = 0.011), ≥ 2 servings of fish/week (p = 0.002), and a low cholesterol diet (p = 0.034). There were no significant changes in lipid levels over the 6 months among nutrition counseling patients. When comparing nutrition counseling patients to those who were referred but did not attend, we found at 6 months a higher percentage of nutrition counseling patients followed a high-fiber diet (p=0.03), consumed 2 or more servings of fish per week (p=0.01), followed a low-cholesterol diet (p = 0.03), and achieved a greater weight loss (p = 0.04) compared to the group that did not attend. Conclusion At six months we found that patient-centered nutrition counseling appears to be effective for promoting changes in nutrient intake, diet habits and weight in SLE patients. However, the counseling did not show a significant improvement in lipid levels, possibly due to short follow-up and/or lupus related factors.

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“…One full‐text was excluded as the study participants with chronic conditions were not using corticosteroids, leaving three included studies that were published between 2009 and 2017. These mainly reported on work undertaken in Anglo‐American contexts (the United Kingdom and United States).…”

Section: Resultsmentioning

confidence: 99%

Obesity prevention in corticosteroid‐treated patients: Use and effectiveness of strategies for weight management

Conklin

Hong

2019

Clinical Obesity

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Summary We conducted a systematic review to identify the use and effectiveness of clinical interventions to prevent or mitigate weight gain in patients using systemic corticosteroids. We independently searched nine bibliometric databases for reviews and longitudinal studies published up to 26 October 2018, and assessed the quality of studies meeting inclusion criteria. We identified 3893 records and screened 3037 eligible studies, read four full‐texts and extracted data from three randomized control trials. Two studies examined a diet‐only intervention for weight management, while one study examined a mixed intervention for diet and exercise. Overall, existing evidence is of poor quality and based on small feasibility studies of either paediatric leukaemia or female lupus patients, which suggested divergent effects of lifestyle interventions on weight, body mass index or waist circumference. Current evidence suggests a state of clinical equipoise that deserves greater research attention given the prevalent use of corticosteroids for treating a variety of chronic conditions. Robust high‐quality longitudinal studies to decipher preventive strategies of steroid‐induced weight gain must be prioritized in research and policy to improve patient care and prevent further obesity‐related disease burden.

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Weight loss and improvements in fatigue in systemic lupus erythematosus: a controlled trial of a low glycaemic index diet versus a calorie restricted diet in patients treated with corticosteroids

Cited by 61 publications

References 28 publications

Bariatric surgery outcomes in patients with systemic lupus erythematosus

Bariatric surgery outcomes in patients with systemic lupus erythematosus

Short-term patient-centered nutrition counseling impacts weight and nutrient intake in patients with systemic lupus erythematosus

Obesity prevention in corticosteroid‐treated patients: Use and effectiveness of strategies for weight management

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