Weight loss and changes in generic and weight-specific quality of life in obese adolescents

Patrick, Donald L.; Skalicky, Anne; Edwards, Todd C.; Kuniyuki, Alan; Morales, Leo S.; Leng, Mei; Kirschenbaum, Daniel S.

doi:10.1007/s11136-010-9824-0

Cited by 28 publications

(35 citation statements)

References 17 publications

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“…Moreover, little is known about the effects of intensive lifestyle treatment on the different domains of HRQoL [12]. Such knowledge can provide valuable information on the effectiveness of these treatments in children and adolescents with severe obesity [19]. …”

Section: Introductionmentioning

confidence: 99%

Health-Related Quality of Life in Children and Adolescents with Severe Obesity after Intensive Lifestyle Treatment and at 1-Year Follow-Up

et al. 2018

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Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL. Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI. Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains. Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

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Section: Introductionmentioning

confidence: 99%

Health-Related Quality of Life in Children and Adolescents with Severe Obesity after Intensive Lifestyle Treatment and at 1-Year Follow-Up

et al. 2018

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“…Although the PHS measures had not been previously validated for this specific population, they have been used extensively and validated in other studies that have included Latino youth [14,19,25,34-39]. All study materials were designed to be readable and understandable for a 5 th grade level.…”

Section: Research Methods and Procecuresmentioning

confidence: 99%

“…Numerous studies have also examined the association between obesity and various self-reported perceived health status (PHS) measures, including general health [14, 15], body shape satisfaction [16-19], physical function [14], depressive symptoms [16, 20-22], and quality of life [14, 23-25]. A potential mechanism explaining the association between obesity status and depressive symptoms, for example, involves physical health, such that adolescents with a higher body mass index (BMI) report significantly lower levels of general health [21,22].…”

Section: Introductionmentioning

confidence: 99%

“…Studies that examined the association between various psychosocial factors and risk of overweight among adolescents found that low life satisfaction, body dissatisfaction, weight concerns, and use of unhealthy weight control behaviors may also increase risk of adolescent overweight [15,16]. Furthermore, obese youth consistently report having a lower quality of life [14,23], which has been found to improve upon weight loss [25]. These studies provide compelling evidence that PHS measures are valid tools for assessing the association between obesity and specific psychological and psychosocial factors.…”

Section: Introductionmentioning

confidence: 99%

“…They report extensive evidence of the relationship between these psychosocial factors and risk of CAD and provide explanations for the possible behavioral and pathophysiological mechanisms underlying this association [30]. Although several published studies have examined the association between BMI and other PHS measures among adolescents [14-25], no such studies have been conducted with youths in Mexico.…”

Section: Introductionmentioning

confidence: 99%

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Perceived health status and cardiometabolic risk among a sample of youth in Mexico

et al. 2015

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Purpose To examine differences in self-reported perceived mental and physical health status (PHS), as well as known cardiometabolic risk factors in a sample of normal weight, overweight, and obese Mexican youths. Methods Cross-sectional analysis of 164 youths aged 11-18 years recruited in Cuernavaca, Mexico. Participants completed a self-administered questionnaire that included measures of generic and weight-specific quality of life (QoL), perceived health, physical function, depressive symptoms, and body shape satisfaction. Height, weight and waist circumference were measured and body mass index (BMI) was determined. Fasting blood samples from participants yielded levels of glucose, triglycerides, and cholesterol (total, HDL and LDL). Results Nearly 50% of participants were female, 21% had a normal BMI, 39% were overweight, and 40% were obese. Obese youths reported significantly lower measures of PHS and showed an increase in cardiometabolic risk, compared to normal weight youths. Physical functioning, generic and weight-specific QoL were inversely associated with BMI, waist circumference and glucose. Depressive symptoms were positively correlated with BMI, waist circumference, glucose levels and HDL cholesterol. No correlation was found between PHS and cardiometabolic risk measures after controlling for BMI. Conclusions In this sample of Mexican youths, obesity was associated with a significantly lower PHS and increased cardiometabolic risk.

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Effects of a Diabetes Prevention Program on Type 2 Diabetes Risk Factors and Quality of Life Among Latino Youths With Prediabetes

et al. 2022

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IMPORTANCELatino youths are disproportionately impacted by prediabetes and type 2 diabetes (T2D). Lifestyle intervention is the first-line approach for preventing or delaying T2D among adults with prediabetes. OBJECTIVE To assess the efficacy of a diabetes prevention program among Latino youths aged 12 to 16 years with prediabetes. DESIGN, SETTING, AND PARTICIPANTS This 2-group parallel randomized clinical trial with 2:1 randomization assessed a lifestyle intervention against usual care among Latino youths with prediabetes and obesity with 6-and 12-month follow-up. The study was conducted at YMCA facilities in Phoenix, Arizona from May 2016 to March 2020. INTERVENTION Participants were randomized to lifestyle intervention (INT) or usual care control (UCC). The 6-month INT included 1 d/wk of nutrition and health education and 3 d/wk of physical activity. UCC included 2 visits with a pediatric endocrinologist and a bilingual, bicultural registered dietitian to discuss diabetes risks and healthy lifestyle changes. MAIN OUTCOMES AND MEASURES Insulin sensitivity, glucose tolerance, and weight-specific quality of life (YQOL-W) at 6-and 12-month follow-up. RESULTS A total of 117 Latino youths (mean [SD] age, 14 [1] years; 47 [40.1%] girls) were included in the analysis. Overall, 79 were randomized to INT and 38 to UCC. At 6 months, the INT led to significant decreases in mean (SE) 2-hour glucose (baseline: 144 [3] mg/dL; 6 months: 132 [3] mg/dL; P = .002) and increases in mean (SE) insulin sensitivity (baseline

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Weight loss and changes in generic and weight-specific quality of life in obese adolescents

Cited by 28 publications

References 17 publications

Health-Related Quality of Life in Children and Adolescents with Severe Obesity after Intensive Lifestyle Treatment and at 1-Year Follow-Up

Health-Related Quality of Life in Children and Adolescents with Severe Obesity after Intensive Lifestyle Treatment and at 1-Year Follow-Up

Perceived health status and cardiometabolic risk among a sample of youth in Mexico

Effects of a Diabetes Prevention Program on Type 2 Diabetes Risk Factors and Quality of Life Among Latino Youths With Prediabetes

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