2009
DOI: 10.1016/j.phrs.2009.01.015
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Weight and plasma lipid control by decaffeinated green tea

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Cited by 42 publications
(23 citation statements)
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“…The main active component in green tea, (−)-epigallocatechin-3-gallate (EGCG), has shown inhibitory effects on weight gain in rat models (Ashida et al, 2004;Bose et al, 2008;Chen et al, 2009;Diepvens et al, 2006;Nagao et al, 2009;Richard et al, 2009;Wolfram et al, 2005). In such studies, EGCG was used at high, non-physiologically attainable concentrations; conversely, when lower concentrations of EGCG were used (i.e.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The main active component in green tea, (−)-epigallocatechin-3-gallate (EGCG), has shown inhibitory effects on weight gain in rat models (Ashida et al, 2004;Bose et al, 2008;Chen et al, 2009;Diepvens et al, 2006;Nagao et al, 2009;Richard et al, 2009;Wolfram et al, 2005). In such studies, EGCG was used at high, non-physiologically attainable concentrations; conversely, when lower concentrations of EGCG were used (i.e.…”
Section: Discussionmentioning
confidence: 99%
“…In such studies, EGCG was used at high, non-physiologically attainable concentrations; conversely, when lower concentrations of EGCG were used (i.e. less than 1 μM), it was found that they exert little or negligible effect (Ashida et al, 2004;Bose et al, 2008;Chen et al, 2009;Diepvens et al, 2006;Kato et al, 2008;Nagao et al, 2009;Richard et al, 2009;Wolfram et al, 2005). The results obtained with high EGCG concentrations may not reflect the physiological response of the body to EGCG administration; since under a regular-based consumption in humans, the highest plasma concentration is about 0.7 μM EGCG (Yang et al, 1998).…”
Section: Discussionmentioning
confidence: 99%
“…Both Lep ob/ob and LepR db/db mice have nearly identical metabolic profiles, demonstrating obesity, hyperinsulinemia, hyperglycemia, and elevated total cholesterol levels (Kennedy et al, 2010). Green tea (Richard et al, 2009) and curcumin (Weisberg et al, 2008) are among some of the dietary interventions shown to reduce the severity of diseased phenotype in these models.…”
Section: Models For Studies On Prevention On Metabolic Syndrome and Tmentioning
confidence: 99%
“…In this study, lipid accumulation in 3T3-L1 adipocytes decreased significantly after a 24 h treatment with 10 μM EGCG while cell viability was retained. Richard et al [48], used male-deficient (ob/ob) mice and their lean counterparts (mice C57BL/6J mice) to investigate whether regular decaffeinated green tea intake affected body weight and lipid profiles. GT consumption resulted in significantly lower weight gain in the obese mice and associated cholesterolemia, triglyceridemia, and adiponectin concentrations but did not adversely affect the lean model.…”
Section: Obesity and Diabetesmentioning
confidence: 99%