Weight-adjusted LMWH Prophylaxis Provides More Effective Thrombin Inhibition in Morbidly Obese Pregnant Women

Ismail, Siti Khadijah; Norris, Lucy; O’Shea, Susan; Higgins, John R.

doi:10.1016/j.thromres.2014.04.006

Cited by 10 publications

(8 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Both studies found that weight-based dosing of LWMH was superior to fixed dosing in reversing the increased thrombotic tendency in class III obesity. 100,101 Evidence level 2-…”

Section: Evidence Level 2+mentioning

confidence: 99%

Care of Women with Obesity in Pregnancy

Denison¹,

Aedla²,

Keag³

et al. 2018

BJOG

178

187

View full text Add to dashboard Cite

“…Both studies found that weight-based dosing of LWMH was superior to fixed dosing in reversing the increased thrombotic tendency in class III obesity. 100,101 Evidence level 2-…”

Section: Evidence Level 2+mentioning

confidence: 99%

Care of Women with Obesity in Pregnancy

Denison¹,

Aedla²,

Keag³

et al. 2018

BJOG

178

187

View full text Add to dashboard Cite

“…Pneumatic compressive devices and low molecular weight heparin have use for thromboprophyalxis. 9 Weight reduction in the postpartum period and thereafter must be strongly encouraged for optimal future pregnancy outcomes and wellbeing.…”

Section: Discussionmentioning

confidence: 99%

Pregnancy with super-obesity: an emerging pandemic

Joshi

Mhaske

Barhate

et al. 2016

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

“…The weight or body mass index distribution of the women could also play a role in the variation of thrombin generation observed. In a study of morbidly obese pregnant women, we found a significant increase of endogenous thrombin potential (ETP) compared to normal weight pregnant women (Ismail et al , ). We also found that thrombin generation levels (ETP) had a significant negative correlation with anti‐Xa levels at weight‐adjusted dose of 75 iu/kg tinzaparin ( r = 0·570) ( P < 0·05) but not at fixed dose of 4500 iu tinzaparin ( r = −0·309) ( P = 0·282).…”

mentioning

confidence: 87%