Wegener's granulomatosis in primary care

Paddock, Michael; Lynch, Carolyn; Paska, Lubomyr

doi:10.1258/shorts.2010.010100

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2019

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“…Marked constitutional symptoms such as fever, weight loss, and fatigue add another layer of GPA complexity, ultimately resulting in a delayed diagnosis. The pattern of symptom progression ranges from mild and gradual to rapid life-threatening organ failure [14]. The progression of clinical manifestations in our case was initially attributed to metabolic or infectious causes.…”

Section: Discussionmentioning

confidence: 69%

Look granulomatosis with polyangiitis (GPA) straight in the face: missed opportunities leading to a delayed diagnosis

Rolle

Muruganandam

Jan

et al. 2019

Autoimmun Highlights

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Granulomatosis with polyangiitis (GPA) is a systemic vasculitis with a potential to involve any organ system. It remains an important cause of kidney related morbidity and mortality. Early diagnosis can be difficult and requires high index of suspicion in all patients, but especially in cases with atypical presentation. We report a case with GPA, which was diagnosed only after new and advancing symptoms belied the original diagnosis of bilateral facial palsy and aortic mural thrombus. which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Section: Discussionmentioning

confidence: 69%