Wegener's granulomatosis in pregnancy: A multidisciplinary approach

Zafar, Urooj; Sany, O; Velmurugan, U; Kabukoba, J. J.

doi:10.1080/01443610802234368

Cited by 8 publications

(5 citation statements)

References 3 publications

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“…We reviewed data on 87 pregnancies in 72 women, reported between 1970 and 2017. The pregnancies were divided into four groups: those who had GPA diagnosed during the current pregnancy, 10–27 those who had their GPA diagnosed during the puerperium, 27,28 those with a prior diagnosis and active disease at conception 27,29 and those with a prior diagnosis but inactive disease at conception 27,30–50 (Figure 2).…”

Section: Resultsmentioning

confidence: 99%

Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature

et al. 2019

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The association of granulomatosis with polyangiitis and pregnancy is rare and therapeutic options are limited by the risk of teratogenicity and fetotoxicity. There is a paucity of published literature to guide clinical decision-making in these cases. We report the case of a 26-year-old woman with no medical history who presented at 21 weeks of gestation with a bilateral sudden loss of hearing and erosive rhinitis. The diagnosis of granulomatosis with polyangiitis was confirmed radiologically and biologically. Corticosteroids were not enough to stabilize the disease and she received intravenous immunoglobulins with remission. A successful delivery of a healthy male newborn was done at 36 weeks. A review of all published literature on granulomatosis with polyangiitis in pregnancy between 1970 and 2017 is presented. Trial registration: Not applicable.

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Section: Resultsmentioning

confidence: 99%

Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature

et al. 2019

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“…Three patients died during pregnancy, one each of GPA, MPA and EGPA . Of the 17 surviving patients, 10 had complications such as IUGR, preterm pregnancy and abortion …”

Section: Resultsmentioning

confidence: 99%

Successful treatment outcomes in pregnant patients with ANCA‐associated vasculitides: A systematic review of literature

et al. 2018

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“…Multiple studies reported de novo occurrence of systemic vasculitis presenting with nasal manifestations during pregnancy and postpartum [82][83][84][85][86][87][88][89][90][91][92][93][94][95][96][97][98][99] such that this differential should always be kept in mind when assessing the pregnant patient with atypical nasal symptoms. The influence of pregnancy on established cases of systemic vasculitis was not clear, but a significant proportion did experience exacerbations.…”

Section: Discussionmentioning

confidence: 99%

“…Studies involving systemic vasculitis and pregnancy were again solely case report based (level 4 evidence). There were multiple reports of both Wegener’s granulomatosis (WG) and Churg-Strauss vasculitis (CS) occurring de novo during pregnancy 82-93 or the postpartum period. 94-99…”

Section: Analysis Of Studiesmentioning

confidence: 99%

“…Studies involving systemic vasculitis and pregnancy were again solely case report based (level 4 evidence). There were multiple reports of both Wegener's granulomatosis (WG) and Churg-Strauss vasculitis (CS) occurring de novo during pregnancy [82][83][84][85][86][87][88][89][90][91][92][93] or the postpartum period. [94][95][96][97][98][99] For patients with a previous established diagnosis of systemic vasculitis subsequently becoming pregnant, approximately half of the case reports (48%) documented a flare-up of the disease, 97,99-109 and half were not exacerbated during the time of the pregnancy 98,99,[110][111][112][113][114][115][116] (level 4 evidence).…”

Section: Nasal Tumormentioning

confidence: 99%

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