Wegener's granulomatosis complicating pregnancy

Murty, G. E.; Davison, John M.; Cameron, D. S.

doi:10.3109/01443619009151226

Cited by 11 publications

(2 citation statements)

References 4 publications

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“…We reviewed data on 87 pregnancies in 72 women, reported between 1970 and 2017. The pregnancies were divided into four groups: those who had GPA diagnosed during the current pregnancy, 10–27 those who had their GPA diagnosed during the puerperium, 27,28 those with a prior diagnosis and active disease at conception 27,29 and those with a prior diagnosis but inactive disease at conception 27,30–50 (Figure 2).…”

Section: Resultsmentioning

confidence: 99%

Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature

et al. 2019

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The association of granulomatosis with polyangiitis and pregnancy is rare and therapeutic options are limited by the risk of teratogenicity and fetotoxicity. There is a paucity of published literature to guide clinical decision-making in these cases. We report the case of a 26-year-old woman with no medical history who presented at 21 weeks of gestation with a bilateral sudden loss of hearing and erosive rhinitis. The diagnosis of granulomatosis with polyangiitis was confirmed radiologically and biologically. Corticosteroids were not enough to stabilize the disease and she received intravenous immunoglobulins with remission. A successful delivery of a healthy male newborn was done at 36 weeks. A review of all published literature on granulomatosis with polyangiitis in pregnancy between 1970 and 2017 is presented. Trial registration: Not applicable.

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Section: Resultsmentioning

confidence: 99%

Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature

et al. 2019

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“…WG is rare in pregnancy; to date 42 pregnancies have been reported in 33 patients (including this present case) since first described in 1970 9 – 35. The cases in the literature are described in table 1.…”

Section: Discussionmentioning

confidence: 79%

Wegener's granulomatosis in pregnancy: a case report and review of the medical literature

Devakumar

Castelino²,

Chow³

et al. 2010

Case Reports

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A Caucasian woman in the third trimester of her sixth pregnancy was diagnosed with Wegener's granulomatosis (WG) following investigation for recurrent ear infections and a persistent dry cough. Chest radiograph showed granulomatous lesions and the c-ANCA (antineutrophil cytoplasmic antibody) was strongly positive. She required pulsed methylprednisolone and cyclophosphamide followed by oral prednisolone and azathioprine to control the disease process during and after pregnancy. Neither the disease nor aggressive treatment adversely affected the pregnancy and she delivered a healthy baby girl by elective induction at 37 weeks. A review of the literature on Wegener's granulomatosis in pregnancy is presented.

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Diseases of the Respiratory System

Swiet¹

2002

Medical Disorders in Obstetric Practice

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Wegener's granulomatosis complicating pregnancy

Cited by 11 publications

References 4 publications

Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature

Granulomatosis with polyangiitis and pregnancy: A case report and review of the literature

Wegener's granulomatosis in pregnancy: a case report and review of the medical literature

Diseases of the Respiratory System

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