Wegener's Granulomatosis Causing Bilateral Facial Paralysis and Deafness

Gómez-Torres, Antonio; Zamora, Isabel Tirado; Jiménez, Antonio Abrante; Ortega, Francisco

doi:10.1016/j.otoeng.2013.04.011

Cited by 3 publications

(8 citation statements)

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“…Bilateral simultaneous peripheral facial paralysis occurs frequently as a manifestation of systemic disease. There are many infectious pathogens or diseases in the cause of peripheral facial paralysis, including herpes simplex virus, varicella‐zoster virus, Epstein–Barr virus, cytomegalovirus, HIV, Lyme disease, syphilis, leptospirosis and tuberculosis . In our case, all these infectious causes were found to be negative.…”

Section: Discussionmentioning

confidence: 48%

“…There are many infectious pathogens or diseases in the cause of peripheral facial paralysis, including herpes simplex virus, varicella-zoster virus, Epstein-Barr virus, cytomegalovirus, HIV, Lyme disease, syphilis, leptospirosis and tuberculosis. [6][7][8][9][10] In our case, all these infectious causes were found to be negative. Peripheral facial paralysis due to HIV infection can occur at any stage, but more often in healthy HIV carriers than in patients with AIDS.…”

Section: Discussionmentioning

confidence: 78%

“…There are some interesting reports that reveal different causes for BFP. One patient with bilateral facial paralysis has revealed an association with biopsy‐proven pulmonary sarcoidosis; another patient with hypoacusis and BFP was diagnosed as having Wegener's granulomatosis resistant to immunosuppressive therapy and steroid boluses . Four pediatric patients who developed bilateral facial paralysis as a result of acute otitis media, Lyme disease, recurrent central nervous system leukemia, and acute disseminated encephalomyelitis have been reported …”

Section: Discussionmentioning

confidence: 99%

“…One patient with bilateral facial paralysis has revealed an association with biopsy-proven pulmonary sarcoidosis; another patient with hypoacusis and BFP was diagnosed as having Wegener's granulomatosis resistant to immunosuppressive therapy and steroid boluses. 8,9 Four pediatric patients who developed bilateral facial paralysis as a result of acute otitis 1 Bilateral simultaneous peripheral facial paralysis is less often idiopathic (under 20%) than unilateral facial paralysis (over 50%). 2 Adour et al 7 found only three patients (0.3%) with bilateral facial palsy in their study of 1000 patients.…”

Section: Discussionmentioning

confidence: 99%

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Mask face: Bilateral simultaneous facial palsy in an 11‐year‐old boy

Güngör

Raif

Arslan

2013

Pediatrics International

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Bilateral facial paralysis is an uncommon clinical entity especially in the pediatric age group and occurs frequently as a manifestation of systemic disease. The most important causes are trauma, infectious diseases, neurological diseases, metabolic, neoplastic, autoimmune diseases and idiopathic disease (Bell's palsy). We report a case of an 11-year-old boy presenting with bilateral simultaneous peripheral facial paralysis. All possible infectious causes were excluded and the patient was diagnosed as having Bell's palsy (idiopathic). The most important approach in these cases is to rule out a life-threatening disease.

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Section: Discussionmentioning

confidence: 48%

Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Mask face: Bilateral simultaneous facial palsy in an 11‐year‐old boy

Güngör

Raif

Arslan

2013

Pediatrics International

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“…En muy pocos casos, otros pares craneales están afectados, como el IX, X y XII, lo cual debe tenerse en cuenta al explorar pacientes con GP que cursen con disfonía sin estenosis subglótica (25).…”

Section: Figura 5 Imagen Cortesía Del Servicio De Otorrinolaringologunclassified

Enfoque otorrinolaringológico de la granulomatosis con poliangeítis (de Wegener) Otolaryngologic approach to granulomatosis with polyangitis (Wegener’s)

Ariza

Rojas

2018

Acta otorrinolaringol cir cabeza cuello

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Introducción: La granulomatosis con poliangeítis (de Wegener) es una enfermedad poco frecuente, sin embargo, el 80 a 90% de los casos tienen manifestaciones otorrinolaringológicas, muchas como único síntoma inicial de la enfermedad. Objetivos: El propósito de este artículo es revisar la literatura disponible actualizada sobre granulomatosis con poliangeítis: manifestaciones clínicas, estándares de enfoque, diagnóstico y tratamiento en otorrinolaringología. Diseño: Revisión narrativa de la literatura. Materiales y métodos: Revisión de la literatura mediante búsqueda selectiva por términos MeSH: Otorhinolaryngologic Diseases, Granulomatosis with polyangiitis, Wegener Granulomatosis, de las bases de datos:MEDLINE, Current Contents, Cochrane, Pubmed y Scielo, entre los años 2000 y 2014. Resultados: Se revisaron 39 artículos según los requerimientos de los objetivos. La evidencia científica actual reconoce la importancia del conocimiento sobre granulomatosis con poliangeítis (de Wegener) en otorrinolaringología, para obtener diagnósticos tempranos y ofrecer manejos oportunos. Conclusiones: El diagnóstico y tratamiento tempranos de la granulomatosis con poliangeítis (de Wegener) son las únicas herramientas para mejorar el pronóstico y calidad de vida de los pacientes con esta enfermedad.Introduction: Granulomatosis with polyangiitis (Wegener’s) is a rare disease,however 80% to 90% of the cases have otolaryngologic manifestations, many as initial symptoms of the disease. Objectives: The purpose of this article is to review the current literature about granulomatosis with polyangiitis: Clinic manifestations, approach standards, diagnosis and treatment in otolaryngology. Design: Narrative review. Materials and methods: Literature review by selective search for MeSH terms: Otorhinolaryngologic Diseases, granulomatosis with polyangiitis, Wegenergranulomatosis, in the databases: MEDLINE, Current Contents, Cochrane, PubMed and SciELO, between 2000 and 2014. Results: 39 articles were reviewed according to the requirements of the objectives. Current scientific evidence recognizes the importance of the knowledge about granulomatosis with polyangiitis (Wegener’s) in otolaryngology, in order to give an early diagnosis and to provide an opportune treatment. Conclusions: Early diagnosis and treatment of granulomatosis with polyangiitis (Wegener’s) are the only tools to change the prognosis as well as quality of life of patients with this disease.

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Sequential Bilateral Otitis Media and Bilateral Facial Nerve Paralysis as Presenting Symptoms of Wegener's Granulomatosis

Cerrati

Hartman²,

Gottlieb³

et al. 2013

Journal of Case Reports in Medicine

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Wegener's granulomatosis is an incurable vasculitis that can be life-threatening when end-organ damage occurs. Symptoms most commonly affect the nose, lungs, and kidneys. We present a case study of a 35-year-old male who presented with sequential bilateral otitis media, progressive mixed hearing loss, tinnitus, otalgia, otorrhea, and, later, bilateral facial nerve paralysis despite aggressive antibiotic intervention. The accompanying review of the literature demonstrates only six other patients worldwide with these presenting symptoms. Treatment options and outcome will be discussed.

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Wegener's Granulomatosis Causing Bilateral Facial Paralysis and Deafness

Cited by 3 publications

References 11 publications

Mask face: Bilateral simultaneous facial palsy in an 11‐year‐old boy

Mask face: Bilateral simultaneous facial palsy in an 11‐year‐old boy

Enfoque otorrinolaringológico de la granulomatosis con poliangeítis (de Wegener) Otolaryngologic approach to granulomatosis with polyangitis (Wegener’s)

Sequential Bilateral Otitis Media and Bilateral Facial Nerve Paralysis as Presenting Symptoms of Wegener's Granulomatosis

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