Wegener Granulomatosis: Otologic Manifestation as First Symptom

Abstract

Introduction Wegener granulomatosis is a systemic vasculitis affecting small and medium-sized vessels of the upper and lower respiratory tract and kidneys. Objective To describe a case of Wegener disease with atypical manifestation. Resumed Report We describe the case of a 50-year-old woman with chronic otitis media and sensorineural hearing loss as the primary symptoms, without other manifestations. Conclusion In cases of acute ear manifestations with or without hearing loss and with poor response to usual treatments, Wegener granulomatosis should be included among the possible etiologies. After adequate diagnoses and treatment of this rare disease, there was favorable evolution.

Clinical Manifestations of Wegener Granulomatosis in Iranian Ethnicities Using the K-Means Algorithm: A Descriptive Study

“…In another study, 2 the results showed that the average age at diagnosis was between 20 and 40 years, that males are more affected than females, and that the initial manifestations were in the ear, nose and throat, lung, skin, and kidney. In the present study, the average age at diagnosis was of 42 years, and female patients were more affected than male subjects.…”

“…This helps in the diagnosis of the disease, because, if the patient presents involvement of the left ear, we can diagnose WG more quickly. 2 …”

“… 1 It appears with clinical symptoms that include recurrent respiratory infection, renal manifestations, and nonspecific systemic symptoms. 2 …”