Abstract:Background
Preventive strategies for invasive aspergillosis (IA) have still not been determined in heart transplant recipients whereas IA leads to a high mortality rate at 12 months posttransplantation. The use of voriconazole or echinocandins was proposed but can favor emergence of Aspergillus or Candida sp. resistant strains or promote neurological and liver disorders in some patients.
Objectives
To assess whether universal prophylaxis with weekly high‐dose of liposomal amphotericin‐B (L‐AmB) can safely prev… Show more
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