Weekly Administration of Prostaglandin E2 Gel Compared With Expectant Management in Women With Previous Cesareans

Rayburn, William F.; Gittens, Lisa; Lucas, Michael J.; Gall, Stanley A.; Gómez-Martín, M. Esther

doi:10.1097/00006250-199908000-00018

Cited by 3 publications

(12 citation statements)

References 12 publications

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“…Using a best‐evidence approach, 14 2 RCTs 15,16 and 12 observational 17–28 studies of fair quality were included in analyses (see Table 1). Details of studies excluded can be found elsewhere 9…”

Section: Resultsmentioning

confidence: 99%

“…One study did not report the drug used for induction 17 . Only two studies of oxytocin reported data on use for induction separate from data on use for augmentation 15,16 . Of the two RCTs, one assessed mifepristone and the other PGE2 15,16 .…”

Section: Resultsmentioning

confidence: 99%

“…Only two studies of oxytocin reported data on use for induction separate from data on use for augmentation 15,16 . Of the two RCTs, one assessed mifepristone and the other PGE2 15,16 . While the protocols for the doses of drugs used for induction were reported in most studies, the actual doses used (mean, range, maximum) were not well reported.…”

Section: Resultsmentioning

confidence: 99%

“…Eight fair observational studies and two fair RCTs reported data on CD rates for TOL with augmentation or induction using oxytocin, PGE2 or mifepristone 15,16,18,20–22,24–26,28 . No good or fair quality studies of non‐drug methods of induction were found.…”

Section: Resultsmentioning

confidence: 99%

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The benefits and risks of inducing labour in patients with prior caesarean delivery: a systematic review

McDonagh

Osterweil

Guise

2005

BJOG

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The benefits and risks of inducing labour in patients with prior caesarean delivery: a systematic reviewObjective To evaluate the risks and benefits of inducing labour in women with a prior caesarean delivery.Design Systematic review.Sample Pregnant women with prior caesarean delivery.Methods Studies were identified using MEDLINE, EMBASE, HealthSTAR, Cochrane Database of Systematic Reviews, Cochrane Controlled Trials Register, Database of Abstracts of Reviews of Effectiveness, reference lists and experts. Main outcome measures All studies reporting data for outcomes in women with induced labours and prior caesarean were eligible. Methodologic quality was evaluated using the criteria of the U.S. Preventive Services Task Force and the NHS Centre for Reviews and Dissemination. We assigned studies good, fair or poor rating. Results We reviewed 162 full text articles, identified 14 fair-quality studies, and found no good-quality studies.Compared with spontaneous labour, induction was more likely to result in caesarean delivery. Of women undergoing spontaneous labour, 20% had a caesarean (range 11-35%) compared with 32% receiving oxytocin (range 18 -44%). In studies of PGE2, spontaneous labour resulted in caesarean delivery in 24% (range 18 -51%) compared with 48% with PGE2 (range 28 -51%). There was a non-significant increase in uterine ruptures among those induced compared with spontaneous labours. There were no maternal deaths; other maternal complications were infrequently reported. Only four studies reported on infant deaths; other infant outcomes were inadequately reported. Conclusion Women with a history of caesarean attempting trial of labour who require induction have a higher rate of caesarean delivery and have a slightly elevated risk of rupture compared with similar women with spontaneous labour. More consideration is needed for potential confounders: dose, reasons for induction and appropriate comparison groups.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

The benefits and risks of inducing labour in patients with prior caesarean delivery: a systematic review

McDonagh

Osterweil

Guise

2005

BJOG

View full text Add to dashboard Cite

show abstract

“…Rayburn et al. (1999) randomized 294 women to either receive a weekly dose of 0·5 mg intracervical prostaglandin E2 gel from 39 to 41 weeks or be managed expectantly.…”

Section: Resultsmentioning

confidence: 99%