“…This tendency was also observed by other authors 3 , 4 , 6 , 11 , 13 , 20 – 22 . The hemolytic disease seems to make cholecystolithiasis manifest at an earlier age, unrelated to obesity, and more frequently in males 23 – 26 . Interestingly, even patients with hematological disease can present cholesterol stones, which shows that factors may overlap in the formation of these stones in hemolytic anemias 25 , 26 .…”