The article is devoted to studying the characteristics of the atmosphere over the Yenisei riverbed with the help of a drone. We develop special mounted measuring equipment for the drone for experimental observations. Designed equipment was used to measure weather parameters and atmospheric pollution from autumn 2020 to summer 2021. More than 50 drone flights were performed during this time. The experiments obtained data from measurements of temperature, relative humidity, and PM25 concentration at different heights above the riverbed. At the same time, no quasi-stationary gradients of meteorological quantities predicted in several publications were found.