Wearable tesla valve-based sweat collection device for sweat colorimetric analysis

Shi, Huanhuan; Cao, Yu; Zeng, Yining; Zhou, Yanuo; Wen, Weihua; Zhang, Congxuan; Zhao, Yuchao; Chen, Zhe

doi:10.1016/j.talanta.2022.123208

Cited by 50 publications

(38 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, since tears include many biomarkers, contact lens sensors can be used to directly measure different parameters such as glucose, urea, protein concentrations, ions [ 112 ], IOP, and corneal temperature, noninvasively. Microelectromechanical machining technology [ 113 ] enables contact lenses with detection electrodes and tiny structures to be used as wearable devices for biomarkers monitoring and delivery of drugs for treating eye diseases [ 114 ]. The combination of eyeball physiological information monitoring and drug delivery system will become the trend of personalized ophthalmic disease diagnosis and treatment [ 115 ].…”

Section: In Vitro Biomechanical Study Methods Of Eye Tissuementioning

confidence: 99%

Biomechanical analysis of ocular diseases and its in vitro study methods

Zhao

Yan

et al. 2022

BioMed Eng OnLine

Self Cite

View full text Add to dashboard Cite

Ocular diseases are closely related to the physiological changes in the eye sphere and its contents. Using biomechanical methods to explore the relationship between the structure and function of ocular tissue is beneficial to reveal the pathological processes. Studying the pathogenesis of various ocular diseases will be helpful for the diagnosis and treatment of ocular diseases. We provide a critical review of recent biomechanical analysis of ocular diseases including glaucoma, high myopia, and diabetes. And try to summarize the research about the biomechanical changes in ocular tissues (e.g., optic nerve head, sclera, cornea, etc.) associated with those diseases. The methods of ocular biomechanics research in vitro in recent years are also reviewed, including the measurement of biomechanics by ophthalmic equipment, finite element modeling, and biomechanical analysis methods. And the preparation and application of microfluidic eye chips that emerged in recent years were summarized. It provides new inspiration and opportunity for the pathogenesis of eye diseases and personalized and precise treatment.

show abstract

Section: In Vitro Biomechanical Study Methods Of Eye Tissuementioning

confidence: 99%

Biomechanical analysis of ocular diseases and its in vitro study methods

Zhao

Yan

et al. 2022

BioMed Eng OnLine

Self Cite

View full text Add to dashboard Cite

show abstract

“…On the other hand, Shi et al developed a wristband in the form of a sensor to detect pH and glucose in sweat with an integrated hydrophobic microfluidic device consisting of Tesla valves and absorbent pads (filter paper) [ 136 ] as shown in Figure 11 b. The PDMS channel was treated with a polyvinylpyrrolidone (PVP) ethanol solution and silica gel to create a hydrophilic surface and increase the capillary force for sweat collection.…”

Section: Sweat-sensing Device (Ssd)mentioning

confidence: 99%

“… Sweat-sensing device for continuous flow ( a ) The epidermal patch of hydrophobic microfluidic device [ 180 ] (reused with the permission of copyright 2018, John Wiley and Sons) ( b ) The epidermal patch of hydrophilic microfluidic device mounted with absorbent material. Reprinted from [ 136 ], copyright (2022), with permission from Elsevier. ( c ) The wearable patch of the CF of hydrophobic microfluidic device embedded with paper and hydrogel to measure sweat lactate [ 182 ].…”

Section: Sweat-sensing Device (Ssd)mentioning

confidence: 99%

See 1 more Smart Citation

A Comprehensive Review of the Recent Developments in Wearable Sweat-Sensing Devices

Ibrahim

Sabani

Johari

et al. 2022

Sensors

View full text Add to dashboard Cite

Sweat analysis offers non-invasive real-time on-body measurement for wearable sensors. However, there are still gaps in current developed sweat-sensing devices (SSDs) regarding the concerns of mixing fresh and old sweat and real-time measurement, which are the requirements to ensure accurate the measurement of wearable devices. This review paper discusses these limitations by aiding model designs, features, performance, and the device operation for exploring the SSDs used in different sweat collection tools, focusing on continuous and non-continuous flow sweat analysis. In addition, the paper also comprehensively presents various sweat biomarkers that have been explored by earlier works in order to broaden the use of non-invasive sweat samples in healthcare and related applications. This work also discusses the target analyte’s response mechanism for different sweat compositions, categories of sweat collection devices, and recent advances in SSDs regarding optimal design, functionality, and performance.

show abstract

“…It is widely used in various fields, including medicine [ 4 ], chemistry [ 5 ], and biomedicine [ 6 ], etc. In recent years, with the vigorous development of microfluidic technology, microfluidic valves have received extensive attention due to their precise control of microfluidics and low-cost fabrication, such as point-of-care tests (POCT) of tumor marker proteins [ 7 ], unidirectional transport of nanofluids [ 8 , 9 , 10 ], sweat collection microdevice for sweat colorimetric (AST) [ 11 ], rapid and accurate antibiotic-susceptibility testing [ 12 ], etc. A compact and efficient MPV is crucial for the precise manipulation of microfluidics, which directly determines the reliability of the detection results of microfluidic chips.…”

Section: Introductionmentioning

confidence: 99%

Flow Regulation Performance Analysis of Microfluidic Passive Valve for High Throughput Liquid Delivery

Chen

et al. 2022

Micromachines

View full text Add to dashboard Cite

A microfluidic passive valve (MPV) is important for precise flow control, and it determines the reliability of the microfluidic system. In this paper, a novel MPV capable of delivering a constant flow rate independently of inlet pressure changes is proposed. The flow rate of the MPV is adjusted by the difference between the fluid force on the upper surface of the valve core and the spring force. The constant flow rate of the MPV is maintained by automatically changing the size of the gap channel formed by the groove on the valve core and the baffle on the valve body. The nearly constant flow rate of the MPV is 6.26 mL/min, with a variation of 6.5% under the inlet pressure varied from 1.25 kPa to 3.5 kPa. In addition, the flow characteristics of the MPV are analyzed by numerical simulation. With the increase in the inlet pressure, the maximum velocity gradually increases, while the increment of the maximum velocity decreases. In the movement process of the valve core, the region of pressure drop becomes larger. This work has a certain reference value for the design and research of the MPVs with high throughput liquid delivery.

show abstract

Wearable tesla valve-based sweat collection device for sweat colorimetric analysis

Cited by 50 publications

References 36 publications

Biomechanical analysis of ocular diseases and its in vitro study methods

Biomechanical analysis of ocular diseases and its in vitro study methods

A Comprehensive Review of the Recent Developments in Wearable Sweat-Sensing Devices

Flow Regulation Performance Analysis of Microfluidic Passive Valve for High Throughput Liquid Delivery

Contact Info

Product

Resources

About