Wearable Sensors for Supporting Diagnosis, Prognosis, and Monitoring of Neurodegenerative Diseases

Demrozi, Florenc; Borzì, Luigi; Olmo, Gabriella

doi:10.3390/electronics12061269

Cited by 5 publications

(4 citation statements)

References 11 publications

(11 reference statements)

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“…The nervous system plays a critical role in managing and harmonising all the body’s activities, and any disruption or damage to it can result in significant ramifications. 16 Nervous system disorders encompass a wide range of conditions, 17 including mild conditions such as migraines and neuropathy as well as more severe illnesses such as multiple sclerosis, Parkinson’s disease and Alzheimer’s disease. 4 These diseases are considered one of the top 10 main causes of death worldwide in 2020.…”

Section: Discussionmentioning

confidence: 99%

Hospitalisations related to nervous-system diseases in Australia, 1998–2019: a secular trend analysis

Abuhamdah,

Naser

2023

BMJ Open

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ObjectiveThe burden of neurological disease-related disabilities and deaths is one of the most serious issues globally. We aimed to examine the hospitalisation profile related to nervous system diseases in Australia for the duration between 1998 and 2019.DesignA secular trend analysis using a population-based dataset.SettingThis analysis used a population-based study of hospitalised patients in Australia. Hospitalisation data were extracted from the National Hospital Morbidity Database, which collects sets of episode-level information for Australian patients admitted to all private and public hospitals.ParticipantsAll patients who were hospitalised in all private and public hospitalisations.Primary outcome measureHospitalisation rates related to nervous system diseases.ResultsHospitalisation rates increased by 1.04 times (from 650.36 (95% CI 646.73 to 654.00) in 1998 to 1328.90 (95% CI 1324.44 to 1333.35) in 2019 per 100 000 persons, p<0.01). Overnight-stay episodes accounted for 57.0% of the total number of hospitalisations. Rates of the same-day hospitalisation for diseases of the nervous system increased by 2.10-fold (from 219.74 (95% CI 217.63 to 221.86) in 1998 to 680.23 (95% CI 677.03 to 683.43) in 2019 per 100 000 persons). Rates of overnight-stay hospital admission increased by 42.7% (from 430.62 (95% CI 427.66 to 433.58) in 1998 to 614.70 (95% CI 611.66 to 617.75) in 2019 per 100 000 persons). ‘Episodic and paroxysmal disorders’ were the most prevalent reason for hospitalisation, which accounted for 49.0% of the total number of episodes. Female hospitalisation rates increased by 1.13-fold (from 618.23 (95% CI 613.24 to 623.22) in 1998 to 1316.33 (95% CI 1310.07 to 1322.58) in 2019 per 100 000 persons). Male hospitalisation rates increased by 86.4% (from 682.95 (95% CI 677.67 to 688.23) in 1998 to 1273.18 (95% CI 1266.98 to 1279.37) in 2019 per 100 000 persons).ConclusionHospitalisation rates for neurological disorders in Australia are high, potentially owing to the ageing of the population. Males had greater rates of hospitalisation than females.

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Section: Discussionmentioning

confidence: 99%

Hospitalisations related to nervous-system diseases in Australia, 1998–2019: a secular trend analysis

Abuhamdah,

Naser

2023

BMJ Open

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“…For neurodegenerative and cerebrovascular disease patients, continuous health monitoring can drastically improve long-term disease progression, advance quality of life, and prevent complications by enabling early detection and timely intervention. [73][74][75] In this regard, various forms of wearable devices have been developed to allow continuous monitoring of movements, sleep, and relevant biomarkers. [76][77][78][79] Specifically, stretchable strain sensors have been used to detect motion and tremor, despite some limitations such as lack of uniformity or low sensitivity.…”

Section: Monitoring Movement and Sensory Parametersmentioning

confidence: 99%

AI‐Based Metamaterial Design for Wearables

Yigci,

Ahmadpour,

Tasoglu

2023

Advanced Sensor Research

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Continuous monitoring of physiological parameters has remained an essential component of patient care. With an increased level of consciousness regarding personal health and wellbeing, the scope of physiological monitoring has extended beyond the hospital. From implanted rhythm devices to non‐contact video monitoring for critically ill patients and at‐home health monitors during Covid‐19, many applications have enabled continuous health monitorization. Wearable health sensors have allowed chronic patients as well as seemingly healthy individuals to track a wide range of physiological and pharmacological parameters including movement, heart rate, blood glucose, and sleep patterns using smart watches or textiles, bracelets, and other accessories. The use of metamaterials in wearable sensor design has offered unique control over electromagnetic, mechanical, acoustic, optical, or thermal properties of matter, enabling the development of highly sensitive, user‐friendly, and lightweight wearables. However, metamaterial design for wearables has relied heavily on manual design processes including human‐intuition‐based and bio‐inspired design. Artificial intelligence (AI)‐based metamaterial design can support faster exploration of design parameters, allow efficient analysis of large data‐sets, and reduce reliance on manual interventions, facilitating the development of optimal metamaterials for wearable health sensors. Here, AI‐based metamaterial design for wearable healthcare is reviewed. Current challenges and future directions are discussed.

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“…We previously conducted research using a braided piezoelectric poly-l-lactic acid (PLLA) cord [ 12 , 13 ], which has been attracting attention as a wearable sensor [ 14 , 15 , 16 , 17 , 18 , 19 , 20 ]. The braided piezoelectric PLLA cord sensor we have developed to date has many unique features.…”

Section: Introductionmentioning

confidence: 99%

“…For example, a choker with a lucky knot charm can detect only pulsation without being affected by the body’s motion even when the body is making a large motion. When chain stitches are embroidered on a denim fabric, only specific movements of each body part can be detected [ 12 , 13 , 19 , 20 , 27 ]. These results are supported by the findings of analysis with the finite element method (FEM), which identifies the bending displacement of the stitched braided piezoelectric PLLA cord sensor [ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Application of Braided Piezoelectric Poly-l-Lactic Acid Cord Sensor to Sleep Bruxism Detection System with Less Physical or Mental Stress

Tajitsu,

Shimda,

Nonomura

et al. 2023

Micromachines

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For many years, we have been developing flexible sensors made of braided piezoelectric poly-l-lactic acid (PLLA) fibers that can be tied and untied for practical applications in society. To ensure good quality of sleep, the occurrence of bruxism has been attracting attention in recent years. Currently, there is a need for a system that can easily and accurately measure the frequency of bruxism at home. Therefore, taking advantage of the braided piezoelectric PLLA cord sensor’s unique characteristic of being sewable, we aimed to provide a system that can measure the frequency of bruxism using the braided piezoelectric PLLA cord sensor simply sewn onto a bed sheet on which the subject lies down. After many tests using trial and error, the sheet sensor was completed with zigzag stitching. Twenty subjects slept overnight in a hospital room on sheets integrated with a braided piezoelectric PLLA cord. Polysomnography (PSG) was simultaneously performed on these subjects. The results showed that their bruxism could be detected with an accuracy of more than 95% compared with PSG measurements, which can only be performed in a hospital by a physician and are more burdensome for the subjects, with the subjects simply lying on the bed sheet with a braided piezoelectric PLLA cord sensor sewn into it.

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Wearable Sensors for Supporting Diagnosis, Prognosis, and Monitoring of Neurodegenerative Diseases

Abstract: The incidence of neurodegenerative disorders (NDs) is increasing in an aging population [...]

Cited by 5 publications

References 11 publications

Hospitalisations related to nervous-system diseases in Australia, 1998–2019: a secular trend analysis

Hospitalisations related to nervous-system diseases in Australia, 1998–2019: a secular trend analysis

AI‐Based Metamaterial Design for Wearables

Application of Braided Piezoelectric Poly-l-Lactic Acid Cord Sensor to Sleep Bruxism Detection System with Less Physical or Mental Stress

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