Antennas are significant passive components in Microwave Imaging (MWI) system. The proposed work focuses on the design and analysis of a Vivaldi antenna of size 45 × 40 × 1.6 mm 3 for breast cancer diagnosis. The proposed antenna utilizes an FR4 substrate and offers a wideband response. The suggested antenna design is based on a tapered slot antenna. The design utilizes microstrip slot line transition feed as it provides good impedance matching and wide bandwidth. The proposed antenna's design attributes like the radius of the slot and tapering rate are optimized through parametric analysis to achieve desired ultra-wideband (UWB) performance. The UWB offered by the designed antenna is 13.87 GHz (2.79 GHz-16.66 GHz). A Voltage Standing Wave Ratio (VSWR) of less than 2 is obtained for the entire resonating frequency range. The proposed antenna exhibits 60% size reduction compared to the conventional Vivaldi antenna with a peak gain and directivity of 4.77 dBi and 5.84 dBi, respectively. A breast phantom has been designed and simulated for Specific Absorption Rate (SAR) calculation. The designed structure exhibits an average SAR of 0.997 W/kg. Further, the proposed antenna is fabricated and tested. The measured results agree with simulation findings. Hence, the compactness and radiation performance of the proposed antenna makes it suitable for breast cancer diagnosis.