2023
DOI: 10.1038/s41378-022-00443-6
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Wearable and flexible electrochemical sensors for sweat analysis: a review

Abstract: Flexible wearable sweat sensors allow continuous, real-time, noninvasive detection of sweat analytes, provide insight into human physiology at the molecular level, and have received significant attention for their promising applications in personalized health monitoring. Electrochemical sensors are the best choice for wearable sweat sensors due to their high performance, low cost, miniaturization, and wide applicability. Recent developments in soft microfluidics, multiplexed biosensing, energy harvesting devic… Show more

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Cited by 198 publications
(111 citation statements)
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References 144 publications
(253 reference statements)
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“…To overcome these limitations, electrochemical techniques have attracted much attention that offers the convenient detection of toxic metals, advantages of minimal sample pretreatment, economics, rapid ease of detection, robustness, and portability. 15,16 As we all know, differential pulse voltammetry (DPV), cyclic voltammetry (CV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy have been employed for the sensitive determination of trace metal ions in different environment samples. 17,18 However, the electrochemical activity of glassy carbon electrodes (GCE) has poor selectivity, sensitivity, and repeatability to real samples as a result of delayed charge transfer kinetics, interference of coexisting metal ions, and low catalytic activity.…”
Section: Introductionmentioning
confidence: 99%
“…To overcome these limitations, electrochemical techniques have attracted much attention that offers the convenient detection of toxic metals, advantages of minimal sample pretreatment, economics, rapid ease of detection, robustness, and portability. 15,16 As we all know, differential pulse voltammetry (DPV), cyclic voltammetry (CV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy have been employed for the sensitive determination of trace metal ions in different environment samples. 17,18 However, the electrochemical activity of glassy carbon electrodes (GCE) has poor selectivity, sensitivity, and repeatability to real samples as a result of delayed charge transfer kinetics, interference of coexisting metal ions, and low catalytic activity.…”
Section: Introductionmentioning
confidence: 99%
“…With further development, such “swipe, scan, sense, and alert” wearable “lab-on-a-glove” electrochemical sensors may find acceptance and bring drug analysis directly and literally “to the user’s fingertips”, making the facile and safe detection of toxic and dangerous drugs in emergency situations possible and enabling quick, on-site but informed decision making. Wearable flexible electrochemical sensors may find applications in other important fields [ 53 ], potentially making drug detection through monitoring sweat possible.…”
Section: Sensing Using Lab-fabricated or Modified Spe/spe-like Electr...mentioning
confidence: 99%
“…Author details 1 State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, NPU and Shaanxi Joint Laboratory of Graphene, Xi'an, 710072, P. R. China. 2…”
Section: Conflict Of Interestmentioning
confidence: 99%
“…H2O2 is one of the most important metabolic productions and plays a key role in the proliferation, differentiation, and migration of the cells under the physiological conditions 1,2 .…”
Section: Introductionmentioning
confidence: 99%