Wearable Activity Monitors to Support Physical Activity Interventions in Neurodegenerative Disease: A Feasibility Study

Shih, Hai-Jung Steffi; Quinn, Lori; Morgan-Jones, Philippa; Long, Katrina; Schreier, Abigail R.; Friel, Ciarán P.

doi:10.2217/nmt-2022-0028

Cited by 3 publications

(1 citation statement)

References 54 publications

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“…Furthermore, Shih et al employed a four-month coaching program in which participants utilized Fitbit devices and received support through a behavioral intervention aimed at promoting the physical activity, showing the effectiveness of this device [43].…”

Section: Other Therapy (Cognitive and Motor Rehabilitation)mentioning

confidence: 99%

The Role of Innovation Technology in the Rehabilitation of Patients Affected by Huntington’s Disease: A Scoping Review

Maggio,

Billeri,

Cardile

et al. 2023

Biomedicines

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Huntington’s disease is an autosomal dominant neurodegenerative disease caused by the repetition of cytosine, adenine, and guanine trinucleotides on the short arm of chromosome 4p16.3 within the Huntingtin gene. In this study, we aim to examine and map the existing evidence on the use of innovations in the rehabilitation of Huntington’s disease. A scoping review was conducted on innovative rehabilitative treatments performed on patients with Huntington’s disease. A search was performed on PubMed, Embase, Web of Science, and Cochrane databases to screen references of included studies and review articles for additional citations. Of an initial 1117 articles, only 20 met the search criteria. These findings showed that available evidence is still limited and that studies generally had small sample sizes and a high risk of bias. Regarding cognitive rehabilitation, it has emerged that VR- and PC-based methods as well as NIBS techniques are feasible and may have promising effects in individuals with Huntington’s disease. On the other hand, scarce evidence was found for cognitive and motor training that might have a slight impact on overall cognitive function in individuals with Huntington’s disease. Data show that further investigation is needed to explore the effects of innovative rehabilitation tools on cognition, especially considering that cognitive and psychiatric symptoms can precede the onset of motor symptoms by many years.

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Section: Other Therapy (Cognitive and Motor Rehabilitation)mentioning

confidence: 99%

The Role of Innovation Technology in the Rehabilitation of Patients Affected by Huntington’s Disease: A Scoping Review

Maggio,

Billeri,

Cardile

et al. 2023

Biomedicines

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The use of digital outcome measures in clinical trials in rare neurological diseases: a systematic literature review

Poleur

Markati

Servais

2023

Orphanet J Rare Dis

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Developing drugs for rare diseases is challenging, and the precision and objectivity of outcome measures is critical to this process. In recent years, a number of technologies have increasingly been used for remote monitoring of patient health. We report a systematic literature review that aims to summarize the current state of progress with regard to the use of digital outcome measures for real-life motor function assessment of patients with rare neurological diseases. Our search of published literature identified 3826 records, of which 139 were included across 27 different diseases. This review shows that use of digital outcome measures for motor function outside a clinical setting is feasible and employed in a broad range of diseases, although we found few outcome measures that have been robustly validated and adopted as endpoints in clinical trials. Future research should focus on validation of devices, variables, and algorithms to allow for regulatory qualification and widespread adoption.

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Welcome to Volume 14 of Neurodegenerative Disease Management

Paleel

2024

Neurodegener. Dis. Manag.

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Wearable Activity Monitors to Support Physical Activity Interventions in Neurodegenerative Disease: A Feasibility Study

Cited by 3 publications

References 54 publications

The Role of Innovation Technology in the Rehabilitation of Patients Affected by Huntington’s Disease: A Scoping Review

The Role of Innovation Technology in the Rehabilitation of Patients Affected by Huntington’s Disease: A Scoping Review

The use of digital outcome measures in clinical trials in rare neurological diseases: a systematic literature review

Welcome to Volume 14 of Neurodegenerative Disease Management

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