Wear of ultra-high molecular weight polyethylene and polytetrafluoroethylene in a hip simulator: A dose-response study of protein concentration

Good, Victoria; Clarke, Ian C.; Gustafson, Gösta; Downs, Brandon; Anissian, Lucas; Sørensen, Kim

doi:10.1080/000164700317393358

Cited by 41 publications

(27 citation statements)

References 20 publications

(26 reference statements)

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“…With distilled water plus Ostenil ® PTFE wear was lower, with a wear factor of 10 × 10 −6 mm 3 /Nm measured. Previous wear tests of PTFE with distilled water as a lubricant have also shown lower wear than when bovine serum is used [48]. Lubricant uptake by the PTFE control pins was negligible compared with the weight loss due to wear.…”

Section: Discussionmentioning

confidence: 76%

Wear tests of orthopaedic biopolymers with the biolubricant augmented by a visco-supplement

Joyce

2009

Proceedings of the Institution of Mechanical Engineers, Part J:

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The lubricant in which both natural and replacement joints must operate is synovial fluid. In vitro wear tests of such prostheses and their biomaterials generally employ a lubricant based on bovine serum, as this contains proteins that have a critical impact in reproducing clinically valid wear rates in the laboratory. However, it is also recognised that bovine serum is not identical to synovial fluid, a key difference being that synovial fluid includes hyaluronic acid but bovine serum does not. Few clinically valid wear tests employing a lubricant that includes hyaluronic acid have been undertaken, and the results have been contradictory. To try and inform these results, a series of wear tests were undertaken using a clinically validated wear screening device to investigate the influence of the addition of hyaluronic acid to the lubricant on the wear rates on two orthopaedic biopolymers. When a clinically used hyaluronic acid solution, Ostenil ® , was added to a dilute bovine serum lubricant, it was found that wear factors were not greatly changed compared with dilute bovine serum alone. Additional wear tests were undertaken with Ostenil ® added to distilled water. Here, wear was much lower but not clinically valid as transfer films were formed on the test plates.

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Section: Discussionmentioning

confidence: 76%

Wear tests of orthopaedic biopolymers with the biolubricant augmented by a visco-supplement

Joyce

2009

Proceedings of the Institution of Mechanical Engineers, Part J:

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“…The use of saline resulted in the highest wear rate of 0.89 ± 0.08 and 1.23 ± 0.07 mm 3 /Mc (Groups 4 and 5, respectively). The higher wear rate for Group 4 was expected, given that saline lacks any lubricating proteins [30], and yielded the opposite result of polymer on metal articulations [17,18]. Given the lack of evidence for third body wear from the imaging assessment for Group 5 as compared to Group 4, it is believed that slow dissolution of the coating and/or physical removal of the HA coating during specimen handling during testing is responsible for the difference in mass loss; the cycle intervals were decreased to minimize handling of the coated devices.…”

Section: Discussionmentioning

confidence: 89%

“…For example, an increase in the sliding distance a bearing surface travels can result in increased wear [15,16]. Decreasing the quantity of protein in the lubricant can increase the wear rate of UHMWPE on CoCr and decrease the wear rate of PTFE on CoCr, but testing both in a zero protein fluid yields unrealistically low wear rates for both as compared to clinical retrieval analyses [17,18]. In addition, multidirectional or ''cross-shear'' motion can increase the wear rate by an order of magnitude [19][20][21][22] or not have an effect at all [23].…”

Section: Discussionmentioning

confidence: 99%

The use of self-mating PEEK as an alternative bearing material for cervical disc arthroplasty: a comparison of different simulator inputs and tribological environments

Brown

Bao

2012

Eur Spine J

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Purpose The hypothesis for this study was that the simulated wear behavior of a hydroxyapatite coated, selfmating PEEK cervical disc arthroplasty device would be dependent on the simulated testing environment. Methods Five groups of devices were evaluated under suggested ASTM and ISO load and motion profiles. The groups utilized different testing frequencies and protein content of simulator fluid, in addition to assessing the potential for third body wear. The average wear rates were determined using linear regression analysis with a generalized estimating equation. Significant differences between groups were determined using the Wald's test. Results The simulated wear behavior was shown to be highly dependent on the testing environment, where protein content more than decreasing the cyclic loading frequency resulted in increased wear, but was not dependent on the suggested load and motion profiles. It was demonstrated that a self-mating PEEK cervical disc arthroplasty device has wear rates that are similar to existing material combinations for cervical disc arthroplasty. Conclusions This study showed that at a time when data from retrieval analyses is deficient, it is important to test the wear resistance of cervical disc arthroplasty devices under various conditions. Long-term clinical results and ongoing implant retrievals are required for validation between clinical performance and simulator inputs.

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“…However higher friction in most cases does not necessarily imply higher wear and one should evaluate wear behavior independently from friction experiments. Protein adsorption has been previously reported to increase the wear rates of UHMWPE [12,37] as well as decrease them [38,39]. The effect of the denatured layer on the adhesive wear response is the focus of the authors' present research.…”

Section: Contact Angle Measurementsmentioning

confidence: 94%

The effect of protein adsorption on the friction behavior of ultra-high molecular weight polyethylene

Karuppiah

Sundararajan

et al. 2006

Tribol Lett

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Medical-grade UHMWPE samples with two different surface finishing treatments, milling and melting/reforming were exposed to 10% bovine serum albumin solution and their friction responses were quantified using atomic force microscopy. The observed friction increase upon exposure to proteins was attributed to the formation of a layer of denatured proteins on the surface. Changing the crystallinity and surface energy of UHMWPE affected the protein adsorption mechanism and the resulting increase in friction behavior.

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Wear of ultra-high molecular weight polyethylene and polytetrafluoroethylene in a hip simulator: A dose-response study of protein concentration

Cited by 41 publications

References 20 publications

Wear tests of orthopaedic biopolymers with the biolubricant augmented by a visco-supplement

Wear tests of orthopaedic biopolymers with the biolubricant augmented by a visco-supplement

The use of self-mating PEEK as an alternative bearing material for cervical disc arthroplasty: a comparison of different simulator inputs and tribological environments

The effect of protein adsorption on the friction behavior of ultra-high molecular weight polyethylene

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