Weakness in pregnancy – expect the unexpected

Furara, S.; Maw, Min; Khan, Farees; Powell, Kathy

doi:10.1258/om.2008.080011

Cited by 13 publications

(16 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Up to 20% of patients are disabled after 1 year and a maternal mortality of exceeding 10% has been described (nonpregnant GBS has mortality <5%). [ 10 ] Reports before the mid-1980 suggested that GBS in pregnancy carries a high maternal morbidity and mortality. [ 11 ] It was reported that as many as 34.5% of women suffering from GBS during pregnancy required ventilator support.…”

Section: Discussionmentioning

confidence: 99%

Guillain-Barré syndrome complicating pregnancy and correlation with maternal and fetal outcome in North Eastern India: A retrospective study

Sharma

Hussain

et al. 2015

Ann Indian Acad Neurol

View full text Add to dashboard Cite

Background:Guillain-Barré syndrome (GBS) is rare in pregnancy with an estimated incidence between 1.2 and 1.9 cases per 100,000 people annually, and it is generally accepted that it carries a high maternal risk. Most reports of GBS with pregnancy are case reports only.Aim:Purpose of this retrospective study was to find the correlation between pregnancy and GBS.Settings and Design:Records of patients admitted in neurology division were analyzed in a tertiary care teaching hospital in the northeastern Indian pregnant female population with GBS between 15-49 years during the period of 2009-2013.Materials and Methods:We analyzed the records of 47 patients with pregnancy and GBS, evaluated and treated in our institute from August 2009 to December 2013. This is retrospective observational study done in North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), India.Result:Predominant form of GBS was acute inflammatory demyelinating polyneuropathy (AIDP). The weakness started from the lower limbs in majority of patients. Ten percent of women had bifacial weakness. Most of patients had good maternal and fetal outcome. Two patients received intravenous immunoglobulin (IVIG). Only two patient required ventilator supports and one patient had intrauterine death (IUD) and died due to respiratory failure.Conclusion:Our results indicate that risk of GBS increases in third trimester and first 2 weeks after delivery. Demyelinating variety of GBS was common in our population. GBS natural course during pregnancy is mild and showed quick recovery. Maternal and perinatal outcome was good.

show abstract

Section: Discussionmentioning

confidence: 99%

Guillain-Barré syndrome complicating pregnancy and correlation with maternal and fetal outcome in North Eastern India: A retrospective study

Sharma

Hussain

et al. 2015

Ann Indian Acad Neurol

View full text Add to dashboard Cite

show abstract

“…[ 7 ] GBS, in general, has 5% incidence of mortality, but in postpartum, GBS mortality is reported to be higher (10%), emphasizing importance of early diagnosis and rehabilitation. [ 8 ] All three patients were observed to have both anxiety and depression ranging from mild to severe. The reasons were separation anxiety and difficulty in feeding infant other than quadriparesis.…”

Section: Discussionmentioning

confidence: 99%

Guillain–Barre Syndrome in Postpartum Period: Rehabilitation Issues and Outcome – Three Case Reports

Gupta

Patil

Khanna

et al. 2017

Journal of Neurosciences in Rural Practice

View full text Add to dashboard Cite

We report three females who developed Guillain–Barre Syndrome in postpartum period (within 6 weeks of delivery) and were admitted in the Neurological Rehabilitation Department for rehabilitation after the initial diagnosis and treatment in the Department of Neurology. The first case, axonal variant (acute motor axonal neuropathy [AMAN]) had worst presentation at the time of admission, recovered well by the time of discharge. The second case, acute motor sensory axonal neuropathy variant and the third case, AMAN variant presented at the late postpartum period. Medical treatment was sought much later due to various reasons and both the patients had an incomplete recovery at discharge. Apart from their presentations, rehabilitation management is also discussed in some detail.

show abstract

“…It has been reported that as many as 34.5% of women suffering from GBS during pregnancy required ventilatory support whereas our finding is more or less similar to above study 3(27.3%) and one of them died. One study [13] reported that up to 20% of patients are disabled after one year and a maternal mortality of 7%. Whereas the mortality in non-pregnant women is <5%.…”

Section: Discussionmentioning

confidence: 99%

Gullain-Barré Syndrome during pregnancy: Fetomaternal outcomes

Ghimire

Ghimire²,

Ghimire

et al. 2016

J Nobel Med Coll

View full text Add to dashboard Cite

BackgroundGullain-Barre' Syndrome (GBS) is not uncommon during pregnancy in our setting. There are no studies regarding the clinical profile and fetomaternal outcomes of GBS during pregnancy in Nepal. Therefore, this study was conducted to analyse clinical profile and fetomaternal outcome of pregnant women with GBS. Material & MethodsProspective descriptive analysis was carried out of all female's cases of >16 years women of GBS with pregnancy who were admitted in the hospital between 1 st August 2015 and 30 th July 2016. A structured questionnaire was designed which included demographic, obstetric, clinical, neonatal and neurological parameters. Results During the period of 1 year, 11 cases were analysed with median age of 23.7 years. Disease was common in primi and in 3 rd trimester. Three patients (27.2%)needed mechanical ventilation and one of them (9%) died due to ventilator associated pneumonia. There was only one (9%) neonatal death. Conclusion Gullain-Barre' Syndrome is not uncommon in our setting. Early diagnosis and proper management of pregnant women with GBS may result in good fetomaternal outcome.

show abstract

Weakness in pregnancy – expect the unexpected

Cited by 13 publications

References 34 publications

Guillain-Barré syndrome complicating pregnancy and correlation with maternal and fetal outcome in North Eastern India: A retrospective study

Guillain-Barré syndrome complicating pregnancy and correlation with maternal and fetal outcome in North Eastern India: A retrospective study

Guillain–Barre Syndrome in Postpartum Period: Rehabilitation Issues and Outcome – Three Case Reports

Gullain-Barré Syndrome during pregnancy: Fetomaternal outcomes

Contact Info

Product

Resources

About