“…The ring-opening reaction is a common biodegradation pathway of carbazoles. , The ring-opening reaction of the pyrrolic ring (Figure a) can take place during the biodegradation of carbazoles, benzocarbazoles, dibenzocarbazoles, and benzonaphthocarbazoles. The carbazole degrading enzyme is considered to attack the pyrrolic core or aromatic core adjacent to the pyrrolic ring and introduce a hydroxyl or carboxyl group. ,,− In the ring-opening reaction of the pyrrolic ring, the DBE values of N 1 species usually decrease by 1. As a consequence, the abundant N 1 species with DBEs of 9, 12, 15, and 18 may be converted to the abundant N 1 O 1 species with DBEs of 8, 11, 14, and 17, respectively.…”