Weak RHD (Du ) Phenotypic Expression Among the Blood Donors and Recipients in Pesimsr, Kuppam

Abstract

BACKGROUNDRh blood group system is based on the presence or absence of the Rh antigen, often called the Rh factor, on the cell membranes of the red blood cells (erythrocytes).Some red cells possess the D antigen but it is expressed so weakly that the cells are not agglutinated directly by anti-D sera. An indirect antiglobulin test is necessary to identify patients with the Weak D (formerly known as D u ) phenotype. 1 Detecting the Rh blood group as well as D u testing among the Rh-negative individuals is important as the antibodies against Rh antigen can cause transfusion reaction and haemolytic anaemias.