Ways to increase the regenerative potential of mesenchymal stromal cells
O. V. Payushina,
D. A. Tsomartova,
E. V. Chereshneva
et al.
Abstract:The ability of mesenchymal stromal cells (MSCs) to migrate into tissue defects and stimulate regeneration makes them a valuable resource for cell therapy. However, in many cases, in vitro cultivation and the influence of the pathological microenvironment in the patient’s body reduce the viability and therapeutic efficacy of MSCs, so their regenerative potential needs to be strengthened. Preconditioning with hormones, cytokines, various chemical or physical factors, cultivation in a three-dimensional enviro… Show more
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