Wavefront-guided photorefractive keratectomy with and without iris registration: comparison of astigmatic correction

Purpose. To assess the influence of photorefractive keratectomy (PRK) on ocular surface microbial flora. Methods. A prospective study was conducted on patients who underwent PRK. The samples were taken from the inferior conjunctival fornix using a sterile swab, immediately before surgery, and then within three months following the PRK. The samples were tested using three culture mediums including blood agar, chocolate agar, and eosin methylene blue agar. Results. Thirty-five eyes of 35 patients including 19 females (54.3%) with a mean age of 24 ± 3.2 years were enrolled. The culture-positive rate was 15/35 eyes (42.9%) preoperative and 17/35 (48.6%) postoperative samples ( P = 0.47 ). The most common microorganisms isolated from preoperative samples were coagulase-negative Staphylococcus (CoNS) spp. in 14 (40%) samples, followed by Streptococcus spp. in 2 (5.7%), and Staphylococcus aureus in one (2.9%). Postoperative microorganisms isolated from conjunctival samples were CoNS spp. in 15 (42.9%), Streptococcus spp. in 3 (8.6%), and Staphylococcus aureus in one (2.9%), and Corynebacterium spp. in one (2.9%). Conclusion. This study indicated that there is not any remarkable difference in microorganisms isolated from conjunctival samples three months after PRK.

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“…Surgery was performed using a Technolas 217z100 excimer laser system (Bausch & Lomb). PRK protocols were described elsewhere in detail [ 1 , 4 ].…”

Section: Methodsmentioning

confidence: 99%

“…Common short-term complications included pain, delayed visual recovery, and haze. Undercorrection or overcorrection, inability to tolerate contact lenses, light sensitivity, regression, decentration, haze, corneal ectasia, and dry eye are among the most common long-term complications [ 1 – 4 ].…”

Section: Introductionmentioning

confidence: 99%

Ocular Surface Microbial Flora and Photorefractive Keratectomy

Peyman

Bazukar

Narimani

et al. 2022

Journal of Ophthalmology

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“…One of the major concerns after photorefractive keratectomy (PRK) is the development of corneal haziness. [1][2][3][4] Opacification of corneal stroma is a potential complication of PRK that causes reduced contrast sensitivity, glare, and reduced visual acuity (VA). Clinically significant haze occurs in 0.5% to 5.0% of PRK cases.…”

Section: Introductionmentioning

confidence: 99%

Clinical efficacy of Fluorometholone versus Loteprednol eye drops after photorefractive keratectomy: A triple-blinded randomized controlled trial

Razmjoo

Mikaniki

Peyman

et al. 2022

European Journal of Ophthalmology

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Purpose This study aimed to compare the anti-inflammatory efficacy and safety of 0.1% Fluorometholone (FML) versus (vs.) 0.5% Loteprednol etabonate (LE) following photorefractive keratectomy (PRK). Methods A triple-blinded randomized controlled trial was conducted on both eyes of 100 patients with stable refraction who were candidates for PRK. Both eyes in each subject were randomly allocated to the FML or LE groups. The product to be tested was 0.1% FML eye drops packaged in droppers vs. the 0.5% LE sterile ophthalmic suspension (Lotemax®) packaged in identical droppers. The main clinical outcomes were changes in best-corrected distance visual acuity (BCDVA) and corneal optical density. The second clinical outcomes were a change in intraocular pressure (IOP) after the intervention. Results There was no significant difference regarding mean corneal optical density changes between the two groups, one ( P = 0.55) and three months ( P = 0.98) after the intervention. The mean ± SD BCDVA after one month of the intervention was 0.79 ± 0.11 and 0.84 ± 0.11 in LE and FML groups, retrospectively ( P = 0.02). There was no significant difference regarding mean BCDVA between the two groups three months after intervention ( P = 0.21). The IOP showed no significant difference between the two groups after one ( P = 0.18) and three months ( P = 0.53) of the intervention. Conclusions The results of this clinical trial demonstrate that LE and FML treatment was effective with no clinically meaningful effect on IOP following a short course of treatment.

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“…1,3,4 A relatively common concern in patients with a history of RK is residual refractive error and decreasing quality of vision over time. 5,6 Overcorrection or hyperopic shift associated with RK can be attributed to various factors such as cycloplegic refraction preoperatively, incision extension toward the limbus, increased depth or large incisions, longterm use of contact lenses, and eye rubbing or massage postoperatively. This progression can continue for years with increasing age.…”

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confidence: 99%

“…7,8 With the possibility of overcorrection and hyperopic shift in the future, and some surgeons preferring undercorrection to prevent hyperopic shift, leaving some degree of myopia, correcting residual refractive error after RK becomes an important issue for these patients. 6,9…”

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confidence: 99%

Laser Vision Correction after Radial Keratotomy: A Systematic Review and Meta-analysis

Koosha,

Riazi,

Janfaza

et al. 2024

J Cataract Refract Surg

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Laser vision correction for residual refractive errors in patients with previous radial keratotomy (RK) presents a challenging task. Different techniques have been used with varying outcomes. This study aimed to systematically review published manuscripts on refractive surgeries in post-RK patients search in PubMed, Scopus, and Web of Science. The final analysis included 35 studies that described a total of 888 eyes. Our systematic review and meta-analysis demonstrated a significant improvement in uncorrected distance visual acuity (UDVA) for photorefractive keratectomy, topography-guided-PRK, wavefront-guided-PRK, and femtosecond- laser-assisted in situ keratomileusis (LASIK), while mechanical microkeratome LASIK did not yield such significant improvements. Moreover, our results suggest that hyperopic post-RK patients had a significant improvement in UDVA, whereas no such improvement was observed in myopic patients.

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Wavefront-guided photorefractive keratectomy with and without iris registration: comparison of astigmatic correction

Cited by 4 publications

References 21 publications

Ocular Surface Microbial Flora and Photorefractive Keratectomy

Ocular Surface Microbial Flora and Photorefractive Keratectomy

Clinical efficacy of Fluorometholone versus Loteprednol eye drops after photorefractive keratectomy: A triple-blinded randomized controlled trial

Laser Vision Correction after Radial Keratotomy: A Systematic Review and Meta-analysis

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