Wavefront aberrations measured with Hartmann-Shack sensor in patients with keratoconus

Maeda, Naoyuki; Fujikado, Takashi; Kuroda, Toshio; Mihashi, Toshifumi; Hirohara, Yoko; Nishida, Kohji; Watanabe, Hitoshi; Tano, Yasuo

doi:10.1016/s0161-6420(02)01279-4

Cited by 214 publications

(189 citation statements)

References 17 publications

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“…The eyes with keratoconus often have their cones in the inferior part of the cornea, leading to relatively slower wavefront in the inferior part of the cornea and advanced wavefront in the superior area of the cornea. 8 The current study has several weaknesses. First, only 22 eyes were tested in the keratoconus group.…”

Section: Discussionmentioning

confidence: 90%

“…Previous studies also reported that coma and spherical aberrations significantly increased in eyes with keratoconus, with larger increases in coma aberration. [7][8][9][10] Maeda et al 8 found that coma aberration was 2.32 times larger than spherical aberration in eyes with keratoconus, and Barbero et al 9 reported that coma aberration was 3.74 times higher in eyes with keratoconus than in normal controls. In the current study, third-order coma aberration was 3.25 times larger than fourth-order spherical aberration in eyes with keratoconus, and third-order aberration was 6.29 times higher in eyes with keratoconus than in the normal controls.…”

Section: Discussionmentioning

confidence: 99%

“…This result seems to reflect the fact that coma aberration dominates over spherical aberration in eyes with keratoconus. 8 In keratoconus, the apex is usually displaced from the centre of the cornea, resulting in asymmetry in corneal power distribution. The increases in topographic indices such as the inferior-superior 24 and surface asymmetry index 25 values represent the asymmetric power distribution in the cornea, which are in good agreement with the increase in coma aberration in keratoconus.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5][6] In addition, recent studies using wavefront analysis technology showed that ocular and corneal higher-order aberration, particularly coma aberration, is significantly increased in keratoconus. [7][8][9][10] Maeda et al 11 reported that corneal topographic indices significantly correlated with letter-contrast sensitivity in eyes with keratoconus. Applegate et al 7 reported significant correlation between corneal aberration and contrast sensitivity in 91 eyes with a variety of corneal conditions, including 8 eyes with keratoconus, but such correlation in eyes with keratoconus was not assessed.…”

Section: Introductionmentioning

confidence: 99%

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Higher-order wavefront aberration and letter-contrast sensitivity in keratoconus

Okamoto

Samejima

et al. 2007

Eye

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Aims To evaluate the relation between higher-order aberration of the eye and contrast sensitivity function in eyes with keratoconus. Methods In 22 eyes of 14 patients with keratoconus (age 30.578.4 years, means7SD) and 26 eyes of 13 normal controls (age 29.276.7 years), ocular higher-order wavefront aberration for a 6-mm pupil was measured with the Hartmann-Schack aberrometer (KR-9000 PW, Topcon). The root mean square (RMS) of third-and fourth-order Zernike coefficients was used to represent higher-order aberrations. The letter-contrast sensitivity was examined using the CSV-1000LV contrast chart (Vector Vision). Results In the keratoconus group, the letter-contrast sensitivity showed significant correlation with third-order (Spearman's correlation coefficient r ¼ À0.736, Po0.001) and fourth-order aberrations (r ¼ À0.464, Po0.05). There was borderline correlation between log MAR BSCVA and third-order (r ¼ 0.413, P ¼ 0.070) and fourth-order aberrations (r ¼ 0.394, P ¼ 0.086). In the normal group, the letter-contrast sensitivity had no significant correlation with third-order (r ¼ À0.170, P ¼ 0.411) and fourth-order aberrations (r ¼ À0.088, P ¼ 0.673), and log MAR best spectacle-corrected visual acuity (BSCVA) showed no correlation with third-order (r ¼ 0.063, P ¼ 0.762) and fourth-order aberrations (r ¼ À0.282, P ¼ 0.165). Conclusions In eyes with keratoconus, there is significant correlation between contrast sensitivity and ocular higher-order wavefront aberrations.

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Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Higher-order wavefront aberration and letter-contrast sensitivity in keratoconus

Okamoto

Samejima

et al. 2007

Eye

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show abstract

“…A aberrometria ocular tem seu papel destacado em casos de ceratocone para diagnóstico (57,(63)(64)(65)(66) , estadiamento (67) , e avaliação do tratamento realizado (65,(68)(69)(70)(71) . O presente estudo pretende avaliar se os dados objetivos com a aberrometria ocular total podem auxiliar na refratometria manifesta, de modo a proporcionar melhor acuidade visual corrigida com óculos (AVc).…”

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