Water Transport through the Skin of Newborn Infants

Sedin, Gunnar; Hammarlund, K; Nilsson, Gert; På, Öberg; Strömberg, Bo

doi:10.3109/03009738109179207

Cited by 8 publications

(6 citation statements)

References 9 publications

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“…TEWL has also been found to be high when relative humidity is low [53] and during physical activity [54]. TEWL rates further depend on the anatomical location of the measurement [32], temperature, and nutritional status at birth [55].…”

Section: Infant Skin Functionmentioning

confidence: 99%

Infant skin physiology and development during the first years of life: a review of recent findings based on in vivo studies

Stamatas¹,

Nikolovski²,

Mack³

et al. 2010

Intern J of Cosmetic Sci

179

167

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SynopsisInfant skin is often presented as the cosmetic ideal for adults. However, compared to adult skin it seems to be more prone to develop certain pathological conditions, such as atopic dermatitis and irritant contact dermatitis. Therefore, understanding the physiology of healthy infant skin as a point of reference is of interest both from the cosmetic as well as from the clinical point of view. Clinical research on healthy infants is, however, limited because of ethical considerations of using invasive methods and therefore until recently data has been scarce. Technical innovations and the availability of non-invasive in vivo techniques, such as evaporimetry, electrical impedance measurement, in vivo video and confocal microscopy, and in vivo fibre-optic based spectroscopy, opened up the field of in vivo infant skin physiology research. Studies incorporating such methods have demonstrated that compared to adult, infant skin continues to develop during the first years of life. Specifically, infant skin appears to have thinner epidermis and stratum corneum (SC) as well as smaller corneocytes at least until the second year of life. The water-handling properties are not fully developed before the end of the first year and infant SC contains more water and less amounts of natural moisturizing factors. Such findings re-evaluate the old notions that skin is fully matured at birth. Armed with this knowledge, we are in a position not only to better understand infant dermatological conditions but also to design better skin care products respecting the distinct qualities of infant skin. Ré suméLa peau de l''enfant est souvent présentée comme l'idéal cosmé-tique pour des adultes. Cependant, comparé à la peau de l'adulte, elle semble être plus propice au développement de certaines pathologies, comme la dermatite atopique et la dermite de contact. Ainsi, comprendre la physiologie de la peau saine de l'enfant en bas âge est un point de référence intéressant d'un point de vue à la fois cosmétique et clinique. La recherche clinique sur les jeunes enfants avec des méthodes invasives est cependant limitée pour des raisons éthiques rendant jusque récemment les données assez rares. Les innovations techniques et la possibilité de techniques in vivo noninvasives, comme l'évaporimétrie, la mesure d'impédance électri-que, la vidéo microscopie confocale, et la spectroscopie à fibre optique, ont ouvert le champ des recherches sur la physiologie de la peau de l'enfant. Les études utilisant de telles méthodes ont montré que comparativement à l'adulte, la peau de l'enfant continue à se développer pendant les premières années de la vie. De façon spé-cifique, la peau du jeune enfant montre un épiderme et un stratum corneum plus mince ainsi que des cornéocytes plus petits au moins jusqu'à l'âge de 2 ans. Les propriétés cutanées vis-à-vis de l'eau ne sont pas entièrement développées avant l'âge de 1 an et le stratum corneum du jeune enfant contient plus d'eau et des quantités moindres de facteurs naturels d'hydratation. De tels résultats re...

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Section: Infant Skin Functionmentioning

confidence: 99%

Infant skin physiology and development during the first years of life: a review of recent findings based on in vivo studies

Stamatas¹,

Nikolovski²,

Mack³

et al. 2010

Intern J of Cosmetic Sci

179

167

View full text Add to dashboard Cite

show abstract

“…Thus, early in gestation, the amniotic fluid water and electrolytes are believed to pass relatively freely from the infant's skin to the amniotic fluid. That this exchange process may continue, to some extent, later in gestation is suggested by observations that premature infants born after 28-30 weeks of gestation have transepithelial water losses during the first day of life that are up to 15 times higher than those of infants born at term (Sedin et al, 1981). Although the fetal skin has a high density of sweat glands, their contribution to amniotic fluid volume and content is not well established.…”

Section: Production Of Chorionic and Amniotic Fluidsmentioning

confidence: 95%

Amniotic Fluid and the Fetal Mucosal Immune System

Nowicki

Goldblum

2015

Mucosal Immunology

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“…1. Levels of pH, NMF (natural moisturizing factors) and skin hydration depending on the age [25,26] условий, анатомической области, выбранной в качестве места измерения, физической активности и состояния питания, поэтому выводы в различных исследованиях, сравнивающих ТЭПВ детей раннего возраста и взрослых, различаются между собой [34]. Так, в исследовании S. Saijo и соавт.…”

Section: кожа: особенности строения и микроскопической структурыunclassified

Features of the Formation of the Epidermal Barrier and the Use of Emollients in Premature and Young Children

et al. 2019

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The article presents modern data on the features of the structure of the skin and the formation of the epidermal barrier in premature and young children. Information is given regarding changes in the properties of the skin: microrelief, hydration, transepidermal water loss, acidity, content of the natural moisturizing factor, and sebum secretion. Attention is also paid to the role of vernix caseosa in the formation of a mature epidermal barrier and data on the use of emollients are provided.

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Water Transport through the Skin of Newborn Infants

Cited by 8 publications

References 9 publications

Infant skin physiology and development during the first years of life: a review of recent findings based on in vivo studies

Infant skin physiology and development during the first years of life: a review of recent findings based on in vivo studies

Amniotic Fluid and the Fetal Mucosal Immune System

Features of the Formation of the Epidermal Barrier and the Use of Emollients in Premature and Young Children

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