“…The Mezquital Valley aquifer is the most emblematic case because the metropolitan area of Mexico City discharges~60 m 3 /s of non-processed wastewater in the valley and the aquifer recharge is made with part of the wastewater that leads to irrigation channels, which explains the presence of FC and chemical contaminants in the water of the wells of the region [56,[67][68][69]. This situation can be presented in EPG, since all wells evaluated showed a high presence of mesophilic aerobic bacteria (1 × 10 5 CFU/100 mL ± 1.14 × 10 5 ) and fecal contamination, to a lesser or greater degree, with the presence of important species [58,59,70] such as E. coli, Citrobacter freundii, Enterobacter aerogenes, Enterobacter cloacae, Klebsiella oxytoca and Klebsiella pneumoniae, which represents a threat to the population, considering that the water used for human consumption and personal hygiene must be free of pathogenic microorganisms [59]. These bacteria, isolated in wells, produce infections in the central nervous system, the digestive system (Escherichia), the lower respiratory tract, the bloodstream, and the urinary tract (Klebsiella, Enterobacter and Escherichia), and wells are not chlorinated in 88% of houses.…”