Water-Soluble Star Polymer as a Potential Photoactivated Nanotool for Lysozyme Degradation
Lidia Mezzina,
Angelo Nicosia,
Laura Barone
et al.
Abstract:The development of nanotools for chemical sensing and macromolecular modifications is a new challenge in the biomedical field, with emphasis on artificial peptidases designed to cleave peptide bonds at specific sites. In this landscape, metal porphyrins are attractive due to their ability to form stable complexes with amino acids and to generate reactive oxygen species when irradiated by light of appropriate wavelengths. The issues of hydrophobic behavior and aggregation in aqueous environments of porphyrins c… Show more
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